Search Results
Research Funding
The Genomics of Gene Regulation project develops methods to construct predictive, accurate gene regulatory network models using genomic data​​.
… They use the gene expression and functional element data to construct gene regulatory network models, taking advantage … system as the cells transition from one physiologic state to another. They derive and test predictions from the models, … data to understand what elements are controlling what genes, in what cell types. The ability to make accurate …
Talking Glossary
La interacción genes–ambiente se refiere a interrelación de los genes (y en términos más amplios, de la función del genoma) y el entorno fÃsico y social.
… Interacción genes-ambiente … La interacción genes–ambiente se refiere a interrelación de los genes (y en términos más amplios, de la función del genoma) y … La interacción genes–ambiente se refiere a interrelación de los genes (y en términos más amplios, de la función del genoma) y …
Clinical Research
The CLINSEQ® Study seeks to learn about the role that your genes play in your health.
… The CLINSEQ® Study seeks to learn about the role that your genes play in your health. … personal and family health histories. We look at genes related to a variety of conditions, including heart disease, … Our goal is to enroll 1500 participants in the project. So far, we have …
News Release
NIH researchers searched for how the body signals the lack of oxygen in melanoma skin cancer.
… the oxygen and nutrients in the original tumor site, the cancer cells travel to other parts of the body (metastasize) to find more nourishment. … nutrients in many types of cancer. They discovered 40 new genes that are either turned on or off by HIF1α, and 10 genes …
News Release
NHGRI researchers identified 59 genes or gene regions linked to canine athletics.
… researchers reached this conclusion after identifying 59 genes or gene regions linked to canine athletics, including those with roles in endurance, … flow and pain perception. What terriers lacked in sporty genes, they made up for in genes associated with physical …
Staff
Dr. Bell is a senior investigator at the National Human Genome Research Institute's Cancer Genetics and Comparative Genomics Branch.
… She conducted her postdoctoral training at Fox Chase Cancer Center, Philadelphia, before joining Harvard Medical … in ovarian cancer and in malignant mesothelioma as a means to home in on regions of the genome containing putative tumor suppressor genes. While at Massachusetts General Hospital/Harvard …
News Release
NIH has awarded grants of more than $28 million aimed at deciphering the language of how and when genes are turned on and off.
… million aimed at deciphering the language of how and when genes are turned on and off. These awards emanate from the … "There is a growing realization that the ways genes are regulated to work together can be important for understanding disease," … How and When Genes Turn On …
News Release
NIH researchers demonstrated that gene therapy may be the best method for correcting the single faulty gene that causes Niemann-Pick disease, type C1.
… mice with the disease; the treated animals were then found to have less severe NPC1 symptoms. … The disease occurs when a faulty housekeeping gene fails to remove cell waste, like lipids and cholesterol. The … focused on mice that had been bred with a faulty NPC1 gene to model Niemann-Pick disease, type C1. The researchers' goal …
Jobs at NHGRI
Postdoctoral positions are available in the laboratory of Dr. Daphne W. Bell, within the Cancer Genetics and Comparative Genomics Branch of the National Human Genome Research Institute, at NIH.
… in the laboratory of Dr. Daphne W. Bell, within the Cancer Genetics and Comparative Genomics Branch of the … a highly motivated postdoctoral candidate committed to research into the molecular underpinnings of uterine … goal of the laboratory is to identify pathogenic driver genes that underlie the development of the most clinically …
Jobs at NHGRI
Postdoctoral positions are available in the laboratory of Dr. Daphne W. Bell, within the Cancer Genetics and Comparative Genomics Branch of the National Human Genome Research Institute, at NIH.
… in the laboratory of Dr. Daphne W. Bell, within the Cancer Genetics and Comparative Genomics Branch of the … a highly motivated postdoctoral candidate committed to research into the molecular underpinnings of uterine … goal of the laboratory is to identify pathogenic driver genes that underlie the development of the most clinically …