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Staff
William J. Pavan, Ph.D. is the chief of NHGRI's Genetic Disease Research Branch.
… Dr. Pavan's group first discovered the neural crest cell transcription factor SOX10 , which is associated with … Pavan's section discovered that mutations of the HMG-box transcription factor SOX10  result in neural crest stem cell …
Staff
Dr. Paul Meltzer is an adjunct investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
Staff
Dr. Sagar is a staff clinician in the Neurobehavioral Clinical Research Section in Dr. Philip Shaw’s lab at the National Human Genome Research Institute.
Research Funding
MorPhiC aims to develop a consistent catalog of molecular and cellular phenotypes for null alleles for every human gene by using in-vitro multicellular systems.
Virtual Exhibit
The Gene Sweepstakes — or GeneSweep as it became popularly known — was a three-year-long, sweepstakes-style contest organized by British bioinformatician Ewan Birney, Ph.D., of the European Bioinformatics Institute. Scientists participated in the contest by betting on the total number of protein-coding genes that would be identified in the human genome sequence generated by the Human Genome Project.
Educational Resources
Messenger RNA (abbreviated mRNA) is a type of single-stranded RNA involved in protein synthesis.
… mRNA is made from a DNA template during the process of transcription. The role of mRNA is to carry protein …
News Release
A the largest genomics study of clear cell endometrial cancer (CCEC) tumors has identified mutations in the TAF1 gene.
… been previously implicated in CCEC. TAF1 encodes part of a transcription factor complex, which regulates the expression …
News Release
NIH researchers searched for how the body signals the lack of oxygen in melanoma skin cancer.
… and her team will analyze the roles that HIF1α and other transcription factors play in turning genes on and off in …
Fact Sheets
A DNA microarray is a tool used to determine whether the DNA from a particular individual contains a mutation in genes.
Staff
Dr. Francis Collins was a senior investigator in Center for Precision Health Research.
… P, Stitzel ML, Collins FS, Kitzman JO, Parker SCJ. A Transcription Start Site Map in Human Pancreatic Islets … P, Freedman M, Siciliano MJ, Collins FS. Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy …