Search Results
Staff
Dr. Heidi Sofia served as a program director in the Division of Genomic Medicine at the National Human Genome Research Institute from 2010-2023.
… W.G. Phylogeny of the bacterial superfamily of Crp-Fnr transcription regulators: exploiting the metabolic spectrum …
Research Funding
MorPhiC aims to develop a consistent catalog of molecular and cellular phenotypes for null alleles for every human gene by using in-vitro multicellular systems.
News Release
Researchers at the National Institutes of Health and their colleagues have identified genomic variants that cause a rare and severe inflammatory skin disorder, known as disabling pansclerotic morphea, and have found a potential treatment.
… of protein that helps turn genes on and off, known as a transcription factor. The STAT4 protein not only plays a role …
Staff
Dr. David Bodine is the chief of and senior investigator in NHGRI's Genetics and Molecular Biology Branch.
… genome, including epigenetic marks and sites occupied by transcription factors, primarily focusing on cell lines or … state (chromatin accessibility, histone modifications, transcription factor binding, DNA methylation and 3D … stem and progenitor cells reveal overrepresentation of ETS transcription factor binding sites. Genome Res , …
Staff
Stacie Anderson is an associate director in the Office of Scientific Core Facilities and is also the director of the Flow Cytometry Core. ​
… for analyses of functional cellular properties and gene transcription profiles including scRNAseq, as well as high …
Research Funding
A list of current and previous Centers of Excellence in Genomic Science (CEGS) grant awards.
… have been shown to regulate chromatin state and transcription, and intron modifications may affect pre-mRNA … every cell. A major mediator of post-transcriptional gene regulation is the translating ribosome, which comprises three … are highly regulated, although the mechanisms of its regulation are poorly understood. A potential mechanism may …
Staff
Dr. Brian Brooks is an adjunct investigator in NHGRI's Center for Precision Health Research.
Research Funding
The three research domains to be considered for support by the NHGRI Ethical, Legal and Social Implications Research Program.
… Genomics and the Rights of Individuals and Groups Law, Regulation and Policy Governing Genomics Industry, Commerce … examine system-level influences on: the direction and regulation of genomic science, research and technology … decision-making about the use of genomic information. Law, Regulation and Policy Governing Genomics The development and …
Staff
Dr. Stephanie Morris is a program director in NHGRI's Division of Genome Sciences.
… and Hager GL. Complex genomic interactions in the dynamic regulation of transcription by the glucocorticoid receptor. Molecular and … Strahl BD. Histone H3 K36 methylation is associated with transcription elongation in Schizosaccharomyces pombe. …
News Release
A the largest genomics study of clear cell endometrial cancer (CCEC) tumors has identified mutations in the TAF1 gene.
… been previously implicated in CCEC. TAF1 encodes part of a transcription factor complex, which regulates the expression …