Search Results
Clinical Research
The Attention Deficit/Hyperactivity Disorder (ADHD) Genetic Research Study explores the genetic factors contributing to ADHD to improve treatment in the future.
Research Funding
The PAGE Consortium investigates ancestrally diverse populations to gain a better understanding of how genetic factors influence susceptibility to disease.
… relative risks, and distribution of phenotypes associated with particular variants and their environmental …
Talking Glossary of Genetic Terms
Race is a fluid concept used to group people according to various factors including, ancestral background and social identity.
Educational Resources
Genetic epidemiology is a relatively new medical discipline that seeks to understand how genetic factors interact with the environment in the context of disease in populations.
Research Funding
The developmental Genotype-Tissue Expression initiative's goal is to catalog and analyze transcriptional profiles from a wide variety of tissues from the pediatric period, including neonates through adolescents, in a post-mortem setting.
… dGTEx Project will establish a database, data portal, and associated tissue bank with data and samples from a minimum … (NHP dGTEx) Project will establish a resource database and associated tissue bank with data and samples from old world … dGTEx initiative is to establish a resource database and associated tissue bank to study gene expression patterns in …
Genetic Disorders
Hemophilia is a bleeding disorder that slows down the blood clotting process.
… who have hemophilia A have low levels of a blood clotting factor called factor eight (FVIII). People who have hemophilia B have low levels of factor nine (FIX). The two types of hemophilia are caused by … Hemophilia A and B are diagnosed by measuring factor clotting activity. Individuals who have hemophilia A …
News Release
NHGRI researchers seek help from people with Sickle Cell Disease to find the factors - environmental, social and genetic - that impact the severity of symptoms.
… is important to the onset of symptoms and complications associated with SCD. Dr. Koehly's team is also reviewing …
Educational Resources
Gene environment interaction is an influence on the expression of a trait that results from the interplay between genes and the environment.
News Release
NIH researchers identified gene variants that cause a rare syndrome of sporadic fevers, skin rashes and recurring strokes, beginning early in childhood.
… have identified gene variants that cause a rare syndrome of sporadic fevers, skin rashes and recurring … The NIH group first encountered a patient with the syndrome approximately 10 years ago. The patient, then 3 … The primary role for ADA2 protein is as a growth factor. Data from the zebrafish model suggest that this …
News Release
Genomic variants that increase risk of kidney disease are found in nearly one-third of West Africans
A study from researchers at National Institutes of Health (NIH) and their collaborators revealed a significant genetic risk factor for kidney disease in people of West African ancestry.
… their collaborators revealed a significant genetic risk factor for kidney disease in people from Ghana and Nigeria. … us better understand the risk of chronic kidney disease associated with APOL1 variants,” said Adebowale A. Adeyemo, … us better understand the risk of chronic kidney disease associated with APOL1 variants across diverse environments. …