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News Release
The TCGA network describes uterine and bile duct cancer.
… the molecular characteristics of breast cancer by African and European Ancestry. This paper identifies molecular differences by … of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas …
Staff
Dr. Ayo Doumatey is a Research Fellow and Laboratory Manager at NHGRI's Center for Research on Genomics and Global Health.
… obesity and obesity-related traits in populations of African ancestry. One of her research interests is to understand the … molecular mechanisms in metabolically healthy obese African Americans. NPJ Genom Med. 2018 Jan 29; 3:4. doi: … et al. Genome-wide association study identifies African-ancestry specific variants for metabolic syndrome. Mol Genet …
Research Funding
Polygenic RIsk MEthods in Diverse populations (PRIMED) Consortium will work together to develop and implement approaches to integrating extant genotype and phenotype data for the purpose of conducting and disseminating Consortium-wide PRS analyses.
… (PRS) Methods and Analysis for Populations of Diverse Ancestry — Study Sites University of Southern California** … Schaid Polygenic Risk of Disease in Populations of Diverse Ancestry UNC-Chapel Hill Yun Li*, Alexander Reiner, Nancy Cox … Across the Life-Span in Populations of Diverse Ancestry University of California, Los Angeles Bogdan …
Staff
Dr. Daniel Shriner is a researcher in NHGRI's Center for Research on Genomics and Global Health.
… and association with obesity in West Africans and African-Americans. Diabetes 59(6):1549–1554. PMCID: … 2010. Genome wide association of anthropometric traits in African and African derived populations. Hum. Mol. Genet. … association for renal traits among participants of African ancestry reveals new loci for renal function. PLoS Genet ., …
News Release
A new phase of the IGNITE Network will conduct clinical trials of genomic medicine interventions.
… and all three conditions are more common among people of African ancestry than European and Asian descent. Specific African populations have two common mutations in the …
Educational Resources
NHGRI participates in the South By Southwest (SXSW) conference to help increase genomic literacy.
… complex and intertwined relationships between a person's ancestry, ethnicity, and racial identity. So, we ask, is … cancer screenings, tried and true forensic techniques, DTC ancestry sleuthing, and COVID-19 tracking: all ways genomics … stories passed down through generations to taking genetic ancestry tests, we are compelled to know more about our …
Staff
Jie Zhou is a data manager and SAS programmer at NHGRI's Center for Research on Genomics and Global Health.
… Zhou J, McLeod H, Adeyemo A, Rotimi CN. Pharmacogenomics, ancestry and clinical decision making for global populations. … variants with ethnicity-specific effects in African Americans. PLoS Genet. 2014 Mar 6;10(3):e1004190. … new loci associated with body mass index in individuals of African ancestry. Nat Genet. 2013 Jun;45(6):690-6. doi: …
File
… Evaluating the promise of inclusion of African ancestry populations in genomics (January 2020) …
News Release
NHGRI researchers and colleagues are calling for health disparities research that focuses on the microbiome.
… cultural and behavioral factors in people of diverse ancestry, according to the perspective. "We hope that … influence in health disparities can be found among some African American woman, according to the perspective. Research has shown that differences in some African American women's vaginal microbiome may result in …
The Genomics Landscape
In the November 3, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., reflects on the important genomics legacy of the Human Heredity and Health in Africa (H3Africa) program as it comes to an end.
… with the aim of developing a sustainable and collaborative African genomics research enterprise. With most of its … and the UK Wellcome Trust (in strong partnership with the African Society for Human Genetics ), H3Africa has fostered … has provided a highly illustrative model for engaging African scientists to conduct research in Africa in a fashion …