Search Results
Genetic Disorders
Parkinson's disease is a neurological condition that typically causes tremor and/or stiffness in movement
… research studies, called genome-wide association studies (GWAS) are an approach that involves rapidly scanning markers … genetic variations associated with a particular disease. GWAS have been able to identify genetic variations that …
News Release
NHGRI researchers investigated the Behcet's disease using Illumina's Immunochip.
The Genomics Landscape
In the February 3, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., reflects on the December 2021 NHGRI symposium's success in confronting the difficult pasts of eugenics and scientific racism.
… in particular the uses of genome-wide association studies (GWAS) to identity genomic variants associated with complex … about the Earth BioGenome Project , an effort to sequence, catalog, and characterize the genomes of all of Earth’s …
Research Funding
The N​on-Coding Variants Program explores which variants in a region associated with a disease or trait cause the higher risk for the disease or trait
… interpreting variation is a genome-wide association study (GWAS), in which the genomes of thousands of people with and … Stanford University Integration of functional data and GWAS to elucidate genetic basis of disease R01 HG008140 …
News Release
Researchers funded by NIH have completed a detailed atlas documenting stretches of human DNA that influence gene expression.
… Expression (GTEx) Consortium, established to catalog how genomic variation influences how genes are turned … levels. The authors of the study used GTEx data to catalog all known eQTLs in the human genome for the first …
Research Funding
Frequently Asked Questions for IGVF RFAs: RFA-HG-20-043, RFA-HG-20-044, RFA-HG-20-045, RFA-HG-20-046, RFA-HG-20-047
… Can you explain more about the variant/element/phenotype catalog and how it will be developed? The development of this catalog will be a consortium effort. The Modeling Projects … Centers will co-lead a collaboration to develop this catalog. Other projects and centers, including the DACC, will …
Research Funding
The Encyclopedia of DNA Elements (ENCODE) Pilot Project launched in September 2003 to identify all functional elements in the human genome sequence.
… is available through Covance Research Products Inc. (Catalog #MMS-126R) and the TAFII250 antibody is available through Santa Cruz Biotechnology ( Catalog #SC-735 ). The third common antibody recognizes … cells and is available through Santa Cruz Biotechnology (Catalog #SC-345). An antibody against a histone modification …
News Release
An ancient, sexually transmitted dog cancer may provide insights into human cancers because of the similarities in the dog and human immune systems.
… Brian Davis, Ph.D, and colleagues, built a comprehensive catalog of genetic variation of healthy dogs based on the … are continuing to accumulate dog genomes for their catalog, and plan further studies on CTVT, including on dog …
Policy Issues
Synthetic biology is a field of science that involves redesigning organisms for useful purposes by engineering them to have new abilities.
Research Funding
A list of expired funding opportunities from the NHGRI Division of Medicine (DGM).
… Supported or Conducted Genome-Wide Association Studies (GWAS) Release Date: August 28, 2007  Developed following a … consultation process with interested stakeholders, the GWAS data-sharing policy will facilitate the research … community's access to genotype-phenotype datasets from GWAS in a broad array of disease areas.  GWAS Oversight …