Search Results
Fact Sheet
mRNA vaccines inject cells with instructions to generate a protein that is normally found on the surface of SARS-CoV-2, the virus that causes COVID-19.
… that is normally found on the surface of SARS-CoV-2, the virus that causes COVID-19.  The protein that the person … response without a person ever having been exposed to the virus that causes COVID-19. Later, if the person is exposed to the virus, their immune system will recognize the virus and …
Educational Resources
A mutation is a change in a DNA sequence. Mutations can result from DNA copying mistakes made during cell division, exposure to ionizing radiation, exposure to chemicals called mutagens, or infection by viruses.
… Mutation, DNA Sequence, Germ Line, Gene …
Educational Resources
In genomic imprinting the ability of a gene to be expressed depends upon the sex of the parent who passed on the gene.
… In genomic imprinting the ability of a gene to be expressed depends upon the sex of the parent who passed on the gene. … DNA Sequence, Genes, Family Health History, Genealogy, Gene Expression … imprinting is the process by which only one copy of a gene in an individual (either from their mother or their …
Fact Sheet
Early in the COVID-19 pandemic, researchers used state-of-the-art genomic sequencers to quickly sequence the SARS-CoV-2 virus.
… genomic sequencers to quickly sequence the SARS-CoV-2 virus. This sequence was quickly shared with other … allowed researchers from across the globe to analyze the virus and better understand how it causes disease. The speed … vaccine candidate. The spike protein is essential for the virus to attach to the host cell, thereby making it an …
News Release
NIH researchers have created a data resource show how differences in an individual's genome can affect gene activity and contribute to disease.
… differences in an individual's genomic make-up can affect gene activity and contribute to disease. The new resource … It gives us unique insights into how people differ in gene expression in tissues and organs." NIH launched the GTEx … that a variant that affects the activity of two genes associated with blood pressure had a stronger effect on gene …
News Release
NIH researchers identified a novel role for a gene known as heat shock protein 60, finding it is critical in tissue regeneration and wound healing.
… of Health researchers have identified a novel role for a gene known as heat shock protein 60 ( Hsp60 ), finding that … "This study proposes an unusual role for a well-known gene," said Shawn Burgess, Ph.D., head of NHGRI's … today in the journal npj Regenerative Medicine . "This gene is found in every organism from bacteria to man. We have …
Research at NHGRI
The Metabolic Medicine Branch houses clinical and laboratory research programs that focus on the development of new therapies for patients with genetic disorders.
… Our investigators and their research teams develop gene addition therapy and gene editing approaches to treat metabolic disorders, study …
Educational Resources
A genotype is an individual's collection of genes.
… BB, Bb, bb could be used to represent a given variant in a gene. Genotypes can also be represented by the actual DNA …
Talking Glossary
Un retrovirus es un virus que utiliza ARN como material genómico.
… Un retrovirus es un virus que utiliza ARN como material genómico. … Un retrovirus es un virus que utiliza ARN como material genómico. Tras la … Un retrovirus es un virus que utiliza ARN como material genómico. …
Educational Resources
A promoter is a sequence of DNA needed to turn a gene on or off.
… A promoter is a sequence of DNA needed to turn a gene on or off. … Deoxyribonucleic Acid (DNA), Enzyme, Gene, Gene Expression, Gene Regulation, Messenger RNA (mRNA), … as related to genomics, is a region of DNA upstream of a gene where relevant proteins (such as RNA polymerase and …