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Educational Resources
Bioinformatics is a subdiscipline of biology and computer science concerned with the acquisition, storage, analysis, and dissemination of biological data.
… storage, analysis, and dissemination of biological data. … Computational Science, Computer Science, Big Data, Biological Data, Bioinformatics … to collect, store, analyze and disseminate biological data and information, such as DNA and amino acid sequences or … storage, analysis, and dissemination of biological data. …
Infographic
An infographic that explains why it was so difficult to fully complete the human genome sequence.
… with a vision. Even with new technologies, genome sequencing is still tough, time-consuming work that requires …
Staff
Chris Wellington is a program director for Computational Genomics and Data Science in the NHGRI Office of Genomic Data Science.
… is a program director for Computational Genomics and Data Science in the NHGRI Office of Genomic Data Science. His primary focus is in the Genome Informatics … the NIH Common Fund Human Microbiome Project and the Big Data to Knowledge initiative. Mr. Wellington received his …
News Release
Micro-sized technologies are among the approaches researchers will use to develop high quality, low cost DNA sequencing technology.
… researchers will use to develop high quality, low cost DNA sequencing technology through new grants from the National … available, are the last to be awarded by the Advanced DNA Sequencing Technology program of the National Human Genome … costs and achieving a high quality of DNA sequencing data." This group of awards is the last for the Advanced DNA …
News Release
The Telomere-to-Telomere (T2T) Consortium has generated the first truly complete sequence of a human Y chromosome - the final human chromosome to be fully sequenced.
… sequence particularly difficult to complete. Assembling sequencing data is like trying to read a long book cut into strips. If … of the human genome, the T2T Consortium applied new DNA sequencing technologies and sequence assembly methods, as …
Research Funding
GS-IT provides sequence analysis tools and software to scientists who rely on genomics in their research.
… Genome Sequencing Informatics Tools (GS-IT) provides "researcher … Genome Sequencing Informatics Tools … Genome Sequencing Informatics Tools …
Talking Glossary
While some sequencing technologies produce reads that are only a few hundred nucleotides long, some methods can generate reads that are thousands to hundreds of thousands of nucleotides long, known as “long-read DNA sequencing.”
… Long-Read DNA Sequencing … While some sequencing technologies produce reads that are only a few … of thousands of nucleotides long, known as “long-read DNA sequencing.” … DNA sequencing technologies determine the order of the base pairs … to assemble the sequences of full chromosomes. While some sequencing technologies produce reads that are only a few 100 …
Secondary Genomics Finding Service
The SGFS can support annotation of up to 2000 exomes/genomes per year on a first-come, first-served basis.
… protocols are in development or under amendment. Sequence data will not be annotated until the SGFS has been able to … Policy for Secondary Findings from Next-Generation Sequencing Research Darnell et al., 2016 Publication … and return of actionable secondary findings in clinical sequencing. Contains the most recent list of genes …
The Genomics Landscape
In the January 2018 edition of The Genomics Landscape, NHGRI Director Eric Green features the NIH Intramural Sequencing Center.
… The NIH Intramural Sequencing Center (NISC) sits on the top floor of a research … houses the Center's state-of-the-art, high-throughput DNA sequencing facility. In a rather modest start in 1997 under … regularly generating large amounts of genome-sequence data and analyses for numerous NHGRI and NIH investigators …
About Genomics
In 2003, an accurate and complete human genome sequence was finished two years ahead of schedule and at a cost less than the original estimated budget.
… the project took on a wide range of other goals, from sequencing the genomes of model organisms to developing new … STSs are helpful in chromosome placement of mapping and sequencing data from many different laboratories. STSs serve as … Human Genome Project, Complete Human Genome Sequencing, Long-range Planning, Gene Expression, Sequence …