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Staff
Dr. Sharon Milgram is an adjunct investigator in the Genetics and Molecular Biology Branch at the National Human Genome Research Institute.
Culture
Work with a talented team, including world-class scientists at NHGRI. Share genomics and its discoveries with the community and the world.
News Release
The Encyclopedia of DNA Elements (ENCODE) Project has created a detailed resource on the letters of life, DNA, identifying genes and regions that may regulate genes in the human and mouse genomes.
… to identify and characterize their functional roles in gene regulation. "A key challenge in ENCODE is that … to turn genes on or off, or tune the exact levels of gene activity, help drive the formation of distinct cell … marks, and new data types, such as long-range DNA interactions and protein-RNA interactions." As a new feature, …
Fact Sheets
A biological pathway is a series of actions among molecules in a cell that leads to a certain product or a change in the cell.
… Other metabolic pathways actually help to build molecules. Gene-regulation pathways turn genes on and off. Such action … hope was based on the success of imatinib (Gleevec), a drug that was specifically designed to treat a blood cancer … in many CML patients. Unfortunately, the one-target, one-drug approach has not held up for most other types of cancer. …
Staff
Dr. Carolyn M. Hutter was the director of the Division of Genome Sciences at the National Human Genome Research Institute.​
… consortia work for genome-wide association studies and on gene-environment interactions for cancer and other complex diseases. Dr. … TA, Green ED. Nat Rev Genet . 2018 Mar;19(3):175-185.  Gene-environment interactions in cancer epidemiology: a National Cancer …
Healthcare Provider Genomics Education Resource
Genomics plays a role in every area of nursing, whether nurses are at the bedside providing one-on-one care, treating entire populations, teaching the next generation of nurses, or making discoveries in the lab.
News Release
The NHGRI Short Course in Genomics brings the latest genomics science to the classroom.
… topics, including genome sequencing, CRISPR and other gene-editing methods, the human microbiome, and ethical and … Lassar said. "Even though we missed out on the casual interactions of an in-person experience, we were able to have …
News Release
Mothers may be able to reduce guilt over their children's inherited obesity guilt by being more careful in the future about their children's diet.
… and the genetic risk factors are complex. They include gene-gene interactions, gene-environment interactions and gene …
Research Funding
Frequently Asked Questions for IGVF RFAs: RFA-HG-20-043, RFA-HG-20-044, RFA-HG-20-045, RFA-HG-20-046, RFA-HG-20-047
… in proposed studies? Although perturbations such as a drug, hormone, or gene knockout may be allowable, these should be used to map … are primarily focused on generation of a resource of gene and regulatory maps while Regulatory Network Projects … is to leverage advances in technology to gain insight into gene regulatory networks. Applications to this RFA should …
CRGGH is now part of the newly-created Metabolic, Cardiovascular, and Inflammatory Disease Genomics Branch.