Search Results
Explainer
Appropriate use of population descriptors in research is a critical scientific issue that is important for advancing genomic science and improving healthcare across human populations.
… used to inappropriately group people into a hierarchical system to "establish and justify systems of power, privilege, … . Race has been used to group people into a hierarchical system that identifies, distinguishes and marginalizes some …
Clinical Research
Post COVID-19 Vaccine Registry for people with mitochondrial disease who have already received the COVID-19 vaccine.
15 Ways Genomics Influences Our World
Genomics is altering a genome with unparalleled efficiency and precision.
… CRISPR recognized that they could borrow tools from the immune system of bacteria  and develop "bacterial scissors" for … Then, it makes copies of itself to infect the person's immune system, making them vulnerable to other infections. CRISPR is …
Policy Issues
Genetic information is used by law enforcement to investigate criminal acts and exonerate those who have been convicted of crimes they did not commit.
… by law enforcement to investigate criminal acts. The legal system also uses genetic information to exonerate those who … The Combined DNA Index System (CODIS) is the Federal Bureau of Investigation’s (FBI) … Combined DNA Index System (CODIS) …
Policies and Guidance
NHGRI does not collect personally identifiable information about you on genome.gov unless you volunteer to provide it.
… assigned to a computer when surfing the Web); Operating system and information about the browser used when visiting … If we store your personal information in a record system designed to retrieve information about you by personal …
News Release
NIH released a Request for Information seeking comments on the data submission and access process for dbGaP.
… of Health (NIH) Genomic Data Sharing Policy establishes a system to promote data sharing, while also protecting … tools, and data management models be developed to make the system as user-friendly and efficient as possible, as well as …
Research Funding
The three research domains to be considered for support by the NHGRI Ethical, Legal and Social Implications Research Program.
… Genomics at the Institutional and System Level Institution and System-based Influences on Genomic Equity System-Level Understanding and Use of Genomics Healthcare … and technologies.  Genomics at the Institutional and System Level This research explores the interplay, …
Clinical Research
A study with the goal of finding the genetic cause of familial Mediterranean fever (FMF) and several novel and undiagnosed causes of autoinflammatory disease.
… while also advancing our understanding of the human immune system. However, a large subset of patients have clinical …
News Release
Over the last 20 years, three families have been unknowingly linked to one another by an unknown illness. Researchers at the National Human Genome Research Institute (NHGRI) and other organizations have now identified the cause of the illness, a new disease called CRIA syndrome. The results of their work were published on Dec. 11 in the journal Nature.
… typical of an autoinflammatory disease, where the immune system appears to be activated without any apparent trigger. … tocilizumab did. Tocilizumab, a drug that suppresses the immune system, reduced the severity and frequency of CRIA syndrome …
Genetic Disorders
Crohn's disease is a chronic inflammatory disorder of the bowel, usually diagnosed in people between the ages of 20 - 30.
… gallstones or other diseases of the liver and biliary system. Both men and women can have Crohn's disease. It can … or steroids (corticosteroids) such as prednisone. Immune system suprressors, such as 6-mercaptopurine or a related …