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News Release
NIH issues a notice seeking public comment on a proposed update to the data management of genomic summary results under the NIH Genomic Data Sharing Policy.
Research at NHGRI
CRGGH facilitates understanding of the relationship between genetic variation and population differences in disease distribution to inform health disparities.
… Its investigators will develop genetic epidemiology models that will explore the patterns and determinants of …
Research Funding
Frequently Asked Questions for IGVF RFAs: RFA-HG-20-043, RFA-HG-20-044, RFA-HG-20-045, RFA-HG-20-046, RFA-HG-20-047
… and the utility of these in generating regulatory network models. What is the difference in scope between the Networks …
News Release
A new study offers insights into why some people's hair goes gray in response to a serious illness or chronic stress.
… NHGRI; Melissa Harris, UAB Researchers used two mouse models in the study. One mouse model carried a mutation that … in these mice caused hair graying. Combining the two mouse models by mating the mice produced greater amounts of gray … they discovered. The researchers then subjected both mouse models to a substance that mimicked a viral infection. The …
File
… Choosing the best models, lessons from diverse complex diseases: Breast Cancer …
News Release
The zebrafish is a powerhouse tool that helps researchers better understand the genes that are implicated in disease.
… "gain-of-function" mutations for core users. "The knock-in models are used for making the exact same mutations as seen …
Event
On August 15-16, the National Human Genome Research Institute (NHGRI), the National Science Foundation (NSF) and the United States Department of Agriculture (USDA) sponsored a meeting Perspectives in Comparative Genomics and Evolution at the Bethesda North Marriott Hotel & Conference Center in Rockville, Maryland.
Profile
Carlos Ferreira, M.D., staff clinician in NHGRI's Metabolic Medicine Branch, knows the catalogue of rare skeletal disorders well. With hundreds of known rare bone disorders and more to be discovered, Dr. Ferreira breaks down the challenges of skeletal genomics.
… and disorders. We are also establishing cell and animal models to study these new genes that are associated with …
Policies and Guidance
Frequently Asked Questions regarding the Update to NIH Management of Genomic Summary Results Access.
… sizes.  Sometimes, GSR can be included in analytical models. For instance, Polygenic Risk Score (PRS) models include scoring files that contain the variants, … for information on the risks and benefits of different models of GSR access. Public input over the years …
Staff
Dr. Michael Erdos is an Associate Investigator in the Molecular Genetics Section of the Center for Precision Health Research.