Search Results
News Release
In a study published in the journal Science, collaborators at NHGRI, the National University of Ireland, Galway, and the Whitney Laboratory for Marine Bioscience at the University of Florida, Augustine, reported that activation of the gene Tfap2 in adult stem cells in Hydractinia can turn those cells into germ cells in a cycle that can repeat endlessly.
… of Hydractinia could provide clues to human reproductive conditions. … system and the formation of reproductive-based conditions and diseases in humans. “By sequencing and …
Fact Sheets
Genetics refers to the study of genes and their roles in inheritance. Genomics refers to the study of all of a person's genes (the genome).
… to the study of genes and the way that certain traits or conditions are passed down from one generation to another. … - in other words, the way that certain traits or conditions are passed down from one generation to another. … Genetics helps individuals and families learn about how conditions such as sickle cell anemia and cystic fibrosis are …
Research Funding
The following are research areas of interest that have been identified by the participating NIH institutes, centers, and offices (ICOs) on the investigator-initiated ELSI Research Grants (R01, R21, R03). Program Officer(s) contact information is also included for each ICO.
… or siblings; returning genetic risks for adult-onset conditions to infants, children, and adolescents; and cascade … the ethical, legal, and social implications of: aspects of neurogenetic research with human participants, such as … misconception, including for rare genetic diseases; neurogenetic research with human nervous system tissue; …
Clinical Research
A study for patients with unexpected genetic results
… about their risk for cancer, heart disease, and other conditions after having genetic testing done for some other … Many of these results are related to cancer risk and heart conditions . If you think you have received a secondary … diagnosis, researchers discover other treatable health conditions …
The Genomics Landscape
In the June 2019 edition of The Genomics Landscape, NHGRI Director Eric Green details the legacy of the Human Microbiome Project as it reaches completion.
… Most of these microbes cannot live outside of the conditions provided by the human body, thus hampering their … this added complexity, iHMP was limited to three disease conditions: preterm birth, onset of inflammatory bowel … metabolic pathways) are gained or lost with these disease conditions. iHMP published a set of papers describing their …
Staff
Dr. Gordon-Lipkin is a researcher and child neurologist with expertise in neurodevelopmental disabilities in the Metabolism, Infection and Immunity (MINI) Section.
… Institute, respectively, where she acquired expertise in neurogenetic and neuroimmune disorders. In 2018, she joined … Her prior work spans multiple neuroinflammatory conditions including autoimmune encephalitis, acute flaccid …
Staff
Dr. Ellen Sidransky is a pediatrician and clinical geneticist in the Medical Genetics Branch at the National Human Genome Research Institute.
Media Advisory
Researchers from the NIH-funded Human Pangenome Reference Consortium will answer questions about a set of papers to be published in the Nature Portfolio journals and Genome Research. The papers and the briefing are under embargo until May 10, 2023, at 11 a.m. E.T.
Clinical Research
A study where both genotypic (individual genetics) and phenotypic (individual disease characteristics) patient data would be analyzed using advanced data-analytics programs to derive meaningful associations for the development of prevention, management and treatment strategies.
… does a thorough examination of any and all of your health conditions. NIH Day 2: Bone marrow biopsy and/or skin … Natural History Study of Hematologic and Premalignant Conditions Associated with RUNX1 Mutation …
Profile
NHGRI researchers recently published a study using virtual reality simulations to investigate how clinicians might use a type of genomic risk information called polygenic risk scores in medical care.
… genomic data in the clinic for diagnosing rare health conditions. But for common health conditions, information such as polygenic risk scores are not … with their polygenic risk scores for several common health conditions. With at-home genomic testing becoming …