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News Release
Researchers build a statistical model using family health history to improve disease risk assessment
Researchers at the National Human Genome Research Institute (NHGRI) have developed a new statistical model that can predict the risk for developing diseases by combining information about family member health and lifestyle factors from family members.
Educational Resources
A carcinogen is an agent with the capacity to cause cancer in humans.
… Cancer, Tumor, Genetic Mutation, Chemical …
Health
Knowledge of your family health history can help you and your healthcare providers identify patterns of inheritance and risk factors.
News Release
Three summer interns advanced biomedical research as part of the NIH Summer Internship Program in Biomedical Sciences.
… This summer, Ms. Iriele focused on patients with Turner syndrome (TS), a chromosomal condition affecting development … student from Cameroon, collected images on Fragile X syndrome from physicians around the world and assessed the … and physical characteristics of Cornelia de Lange syndrome, a developmental disorder that is characterized by …
Staff
Dr. Douglas Stewart is an associate investigator in NHGRI's Center for Precision Health Research.
… studies phenotypes and genetic determinants of familial tumor-predisposition disorders. The goal of his work is to … to characterize novel and under-recognized tumor types associated with the disorder. Dr. Stewart is leading a … pleuropulmonary blastoma (PPB) cancer predisposition syndrome. This disorder represents the first reported cancer …
News Release
Stomach cancers fall into four distinct molecular subtypes researchers with The Cancer Genome Atlas Network have found.
… cells can look under a microscope, even when from the same tumor. The researchers hope that the new classification … study found that the presence of EBV in gastric tumors is associated with a number of other molecular characteristics. … contained frequent amplifications of genes that encode receptor proteins on the outside of the cell, leading to the …
Educational Resources
An oncogene is a mutated gene that contributes to the development of a cancer.
… Carcinogen, Mutagen, Cancer, Cell, Mutation, Tumor Suppressor Gene …
Staff
Dr. Leslie Biesecker is a clinical and molecular geneticist in and the chief of NHGRI's Center for Precision Health Research.
… natural history of numerous diseases, including Proteus syndrome, PIK3CA-related overgrowth syndrome, TARP syndrome, oculofaciocardiodental syndrome, Lenz … studies in the ClinSeq® cohort include discovery of a gene associated with coronary artery calcification using …
Educational Resources
Apoptosis is the process of programmed cell death.
… Programmed Cell Death, Development, DNA Repair, Cancer, Tumor, Cell Division … cell division and the subsequent development of a tumor. …