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… ™ Identification of novel phenotypes • A mild form of type II diabetes mellitus in patients with mutations in GCKR, … traits) • Post-hoc phenotype • ~50% yield of disease • 2-3% of participants • Most undiagnosed • Probably …
The Genomics Landscape
In 2022, The Genomics Landscape spotlighted genomic data sharing each month in a series of entries. This page contains a collection of each of those entries.
… From The Genomics Landscape Originally published: June 2, 2022  Finding a needle in a haystack is never an easy … effort to identify genomic variants that predispose to type 2 diabetes. Nearly 60 other researchers have used this …
Profile
Reflecting on his NIH career, Dr. Smith recounts his journey from researcher to program director in a conversation with NHGRI science writer Sonja Soo, Ph.D. He looks ahead to a retirement filled with traveling, spending time with friends and family, playing pickleball and brewing ale.
… genes and studied conditions such as kidney failure and diabetes. Some high points were performing the analyses … studied conditions such as kidney failure, HIV/AIDS and diabetes. Reflecting on his NIH career, Dr. Smith recounts …
Fact Sheet
Ribonucleic acid (RNA) is an essential molecule that performs many roles in the cell, from carrying the instructions to make proteins to regulating genes.
… in relation to messenger RNAs, or mRNAs, which are a type of RNA that carries the information required for making … is a growing area of research.  Alternative splicing is a type of RNA splicing where different exons are included or … make proteins Messenger RNA, called mRNA for short, is the type of RNA responsible for carrying the instructions for …
The Genomics Landscape
In the August 2019 edition of The Genomics Landscape, NHGRI Director Eric Green recognizes the recipients for the Presidential Early Career Award for Scientists and Engineers (PECASE), the highest honor given by the U.S. Government to outstanding scientists and engineers who are beginning their independent research careers.
… touring North America. Next : September 12, 2019 – January 2, 2020 Turtle Bay Exploration Park Redding, CA After : … if polygenic risk scores are to be clinically actionable; (2) there is a need to investigate ways to integrate other … Heart, Lung and Blood Institute, the National Institute of Diabetes and Digestive and Kidney Diseases, the National …
News Release
A genetic mutation that triggers bladder cancer in dogs is identical to a mutation that is implicated in multiple human cancers.
Media Availability
Researchers find that more than 80 percent of mouse genes had variations in the nearby regulatory DNA that affects gene activity.
… such as height and susceptibility to common diseases like diabetes and heart disease usually stem from a complicated … than from the mother. The findings, reported online March 2, 2015 in the journal Nature Genetics , provide new insights … pervasive allelic balance. Nature Genetics . March 2, 2015, DOI: 10.1038/ng.3222. [ PubMed ] WHO: Jeffrey …
Event
The Genomics and Health Disparities Lecture Series was formed to enhance opportunities for dialogue about how innovations in genomics research and technology can impact health disparities. Topics will range from basic science to translational research.
… Heart, Lung and Blood Institute, National Institute of Diabetes and Digestive and Kidney Diseases and the National …
The Genomics Landscape
In the March 2020 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the newly appointed Dr. Chris Gunter's role as Senior Advisor for Genomics Engagement as well as the 30 oral histories to celebrate the 30th anniversary of the launch of the Human Genome Project.
… gene changes Genetic profile may predict chance of type 2 diabetes among women with gestational diabetes How a tiny and …
The Genomics Landscape
In the August 2021 issue of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., spotlights the NHGRI Extramural Research Program and how it takes a dynamic approach to it's research portfolio to help foster groundbreaking advances in genomics.
… and review processes are often tailored to accommodate the type of high-risk research proposals that will yield the … , which helps people assess their risk for heart disease, diabetes, breast cancer, and colorectal cancer using their …