Search Results
Research at NHGRI
A list of publications led by or in collaboration with the Center for Research on Genomics and Global Health.
… polygenic prediction for kidney function in persons with ancestry from Africa and the Americas. Cell Genom . … of community gatekeepers about genomic risk information in African cleft research. BMC Public Health . 24(1):507. 2024. … risk between major orofacial cleft phenotypes in an African population. Genet Epidemiol . 2024. [ PubMed ]  Zhu …
Research at NHGRI
An international investigation into the genetics of severe acute malnutrition in children.
… skew heavily to represent individuals of European ancestry ( GWAS Diversity Monitor 2023 ). This lack of … novel genetic variants and unique patterns of admixture in African and other diverse ancestry populations who harbor the most genetic diversity. …
Profile
Dr. Hanchard talks about his journey into genetics research, his collaborations with international researchers, and the importance of determination in science.
… the genomics and environmental contributors of diseases in African populations. Diversifying genomics research is at the … Dr. Hanchard studies are more common in individuals of African ancestry. In fact, diversity is at the core of his research …
Fact Sheet
Pharmacogenomics is a growing area of genomic medicine that uses a patient's genomic information to help healthcare providers select the medications and dosages that are predicted to work best in each patient.
… Center, omitting the name for privacy reasons.  “I am an African American woman in my 30s and was recently diagnosed … on data obtained from people with predominantly European ancestry. This means that pharmacogenomic tests may miss …
The Genomics Landscape
In the January 2025 issue of The Genomics Landscape, NHGRI Director Eric Green announces the appointment of Erin Ramos as the new director of the Division of Genome Sciences (DGSci).
… Mapping the relative accuracy of cross-ancestry prediction Lupi, et al. Nat. Comm. , Dec 2024, … participants in genomics studies have primarily European ancestry. The lack of representation of other ancestries … how the accuracy of PRSs varies across different ancestry groups. The researchers found that accuracy was …
About Genomics
A introduction to basic concepts in genomics to help you understand your genome, how it works, and how it impacts your health.
… analyze your DNA and give information about your ancestry, kinship, lifestyle factors and potential disease … on the test, it may reveal some information about your ancestry and the health of you and your family. … various areas, including medical decisions, food safety, ancestry and more. …
Staff
Dr. Elisabeth F. Heuston is a molecular biology and bioinformatics Staff Scientist with the Center for Research on Genomics and Global Health (CRGGH).
… architecture of complex traits among populations of African ancestry. Using her multidisciplinary background, she aims to …
Event
On October 25-29, 2022, the National Human Genome Research Institute (NHGRI) will participate in the ASHG Annual Meeting - the world's largest human genetics and genomics meeting and exposition.
… Traits Quantification of race, ethnicity, and genetic ancestry disparities in anti-hypertensive drug efficacy in … Research Quantification of race, ethnicity, and genetic ancestry disparities in anti-hypertensive drug efficacy in … Genetics and Genetic Epidemiology Developing an African American population-based transcriptome predicion …
The Genomics Landscape
In the February 2, 2023 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., talks about the new NIH Data Management and Sharing (DMS) Policy and how it emphasizes the importance of good data management practices.
… 2022. PMC9793425  One method for studying the ancestry of a human population involves the use of DNA from …  The Smithsonian’s National Museum of African American History and Culture (NMAAHC) will host the … this program, panelists will explore the work of Black and African American millennial scientists conducting …
Genetic Disorders
Thalassemia is a group of inherited diseases of the blood that affect a person's ability to produce hemoglobin, resulting in anemia.
… of Italian, Greek, Middle Eastern, Southern Asian and African Ancestry. The two main types of thalassemia are called … individuals of Southeast Asian, Chinese and Filipino ancestry, results in fetal or newborn death. A child who …