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Jim Mullikin pioneered DNA sequencing technologies during the Human Genome Project and other major advances in genomics.
… Mullikin pioneered DNA sequencing technologies during the Human Genome Project and other major advances in genomics. … What accomplishments in your career are you most proud of? Jim Mullikin: Of course, the Human Genome Project is one of the top ones. I started working on the …
Educational Resources
Shotgun sequencing is a laboratory technique for determining the DNA sequence of an organism's genome.
… sequencing is a laboratory technique for determining the DNA sequence of an organism's genome. … Deoxyribonucleic Acid (DNA), DNA Sequencing, Genome, Human Genome Project … is a laboratory technique for determining the DNA sequence of an organism’s genome. The method involves randomly …
News Release
Research points to the effects of nutrients in how DNA mutates in the mitochondria.
… Research points to the effects of nutrients in how DNA mutates in the mitochondria. … your cells are. The nutrients inside your food create some of the most important molecules in your cells. Scientists are … some vitamins can affect one of these essential molecules, DNA. “You need to create more DNA if you're going to make …
Research at NHGRI
The Democratizing Education for Sickle Cell Disease Gene Therapy project developed patient-focused educational materials for the sickle cell community.
… Education for Sickle Cell Disease Gene Therapy Project, which is led by NHGRI in partnership with other … materials reflect the priorities and perspectives of both individuals living with sickle cell disease and the … gene therapy to understand the benefits and limitations of treatments so that they can make an informed decision on …
Talking Glossary
Scientific racism is a historical pattern of ideologies that generate pseudo-scientific racist beliefs.
… racism. Scientific racism is a historical pattern of ideologies that generate pseudo-scientific racist beliefs. … racism. Scientific racism is a historical pattern of ideologies that generate pseudo-scientific racist beliefs. … in the 19th and early 20th centuries were proponents of such ideologies. By the mid-20th century, …
News Release
Grants are awarded to GTEx project to explore human gene expression and regulation in different tissues, and how genomic variation modulates that expression.
… The National Institutes of Health has awarded eight grants as part of the Genotype-Tissue Expression (GTEx) project to explore how human genes are expressed and … An Atlas of Human Gene Expression The GTEx awards will contribute to a … genomic variants - inherited spelling changes in the DNA code - may influence gene activity and lead to disease. …
News Release
NIH and Inova Health are launching The Genomic Ascertainment Cohort, a pilot project that will examine gene and gene variant influence on phenotypes.
… Databases such as the 1000 Genomes Project and the Exome Aggregation Consortium (ExAC) harbor large numbers of genotypes (an individual's collection of genes). Until now, it has been difficult for researchers … Paradigm To address this challenge, National Institutes of Health and Inova Health System researchers are launching …
News Release
Celebrating 30 years of genomics that has transformed our understanding of life and improved health.
… Celebrating 30 years of genomics that has transformed our understanding of life and improved health. … or swipe over the illustration to zoom. The Human Genome Project (HGP) Timeline contains major milestones in genomics … Photographs taken during the decade-long odyssey of the Human Genome Project. Images include the announcement …
Research Funding
The Knockout Mouse Phenotyping Project (KOMP2) collaborates with the International Mouse Phenotyping Consortium (IMPC) to knockout and characterize all protein-coding genes in the mouse genome.
… Laboratory Knockout Mouse Production and Phenotyping Project (JAX KOMP2) OD023222 Dickinson, Mary E Heaney, Jason D Baylor College of Medicine The BCM Knockout Mouse Production and Phenotyping … Project (BCM KOMP2) HG006348 Lloyd, KC Kent University of California, Davis KOMP2-Phase3 Production and Phenotyping …
Talking Glossary
While some sequencing technologies produce reads that are only a few hundred nucleotides long, some methods can generate reads that are thousands to hundreds of thousands of nucleotides long, known as “long-read DNA sequencing.”
… Long-Read DNA Sequencing … methods can generate reads that are thousands to hundreds of thousands of nucleotides long, known as “long-read DNA sequencing.” … DNA sequencing technologies determine the order of the base … methods can generate reads that are thousands to hundreds of thousands of nucleotides long, known as “long-read DNA …