Search Results
National Advisory Council for Human Genome Research
The Director's Report-Related Documents contain links to materials supplemental to Dr. Eric Green's Director's Report presentation to the National Advisory Council for Human Genome Research in September 2022.
… Genotype-Tissue Expression Project (dGTEx) 20 Capturing RNA Sequence and Transcript Diversity, from Technology … Investigator-Initiated Highlights Smith et al. – “Enrichment Analyses Identify Shared Associations for 25 …
News Release
Researchers find weaker immune response to viral infections in children with mitochondrial disorders
NIH researchers analyzed the gene activities of immune cells in children with mitochondrial disorders and found that their B cells, which produce antibodies to fight viral infections, are less able to survive cellular stress.
… system. Using a genomic technique called single-cell RNA sequencing, which analyzes gene activity in different … a microRNA called mir4485 . MicroRNAs are small strings of RNA that help control when and where genes are turned on and …
Staff
Dr. Mullikin was the former director of the NIH Intramural Sequencing Center (NISC).
… targeted capture methods (Teer et al., Genome Res 2010), RNA sequence analysis, and whole-genome sequence assembly … development, cellular development and cancer progression. RNA sequence analysis is another area of rapid analytical … expression profiles and splice variant differences between RNA extracted from lymphoblastoid cell lines derived from …
Media Advisory
NHGRI hosts a Reddit AMA with Jennifer Doudna, Ph.D., and her research group.
… Learn more about Dr. Doudna's research at http://rna.berkeley.edu/ Contact: Sheena Faherty, Ph.D. NHGRI …
News Release
Research points to the effects of nutrients in how DNA mutates in the mitochondria.
… going to make new cells, and you need to create more RNA for those cells to do their job,” said Lawrence Brody, … are linked to creating the building blocks of DNA and RNA, and not having enough of these vitamins can interfere … going to make new cells, and you need to create more RNA for those cells to do their job. That's the raw material …
The Genomics Landscape
In the February 2, 2023 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., talks about the new NIH Data Management and Sharing (DMS) Policy and how it emphasizes the importance of good data management practices.
… was released in partnership with NHGRI and focuses on RNA biology. The program aims to support projects that pursue … creative, technologically advanced approaches to study RNA function in complex biological systems and that harness RNA research to advance biotechnology. The goal is to …
National Advisory Council for Human Genome Research
The Director's Report-Related Documents contain links to materials supplemental to Dr. Eric Green's Director's Report presentation to the National Advisory Council for Human Genome Research in May 2023.
… Report 17 NASEM Study: Toward Sequencing and Mapping RNA Modifications NASEM RNA Study Website NASEM RNA Workshop Recording NASEM RNA Ideation Challenge 18 Human …
The Genomics Landscape
In the August 6, 2020 edition of The Genomics Landscape, Dr. Eric Green talks about NHGRI's completion of the third phase of the ENCODE Project and how it reveals the most extensive catalog to date of candidate functional elements that may regulate the genes in the human and mouse genomes.
… genome function, the proteins that bind to DNA, and how RNA molecules interact to regulate gene expression. The …
Research at NHGRI
The NIH Intramural Sequencing Center is a multi-disciplinary genomics facility that emphasizes the generation and analysis of DNA sequence.
… of sequencing projects include whole exome sequencing, RNA sequencing, custom capture sequencing, CHiP-seq and whole …
Staff
Dr. Lanata is a staff clinician in NHGRI's Genomics of Autoimmune Rheumatic Disease Section.
… N, Dahl A, Lanata CM , Matloubian M, et al. Single-cell RNA-seq reveals cell type-specific molecular and genetic … Lanata C , Gate RE, et al. Multiplexed droplet single-cell RNA-sequencing using natural genetic variation . Nat …