Search Results
Educational Resources
A retrovirus is a virus that uses RNA as its genetic material.
… Acquired Immunodeficiency Syndrome (AIDS), Cancer, Cell, Deoxyribonucleic Acid (DNA), Genome, … associated with diseases, including AIDS and some forms of cancer. …
News Release
NHGRI appointed Carolyn Hutter, Ph.D., director of the Division of Genome Sciences, which researches human genome function in health and disease.
… research programs. Most recently, she co-managed The Cancer Genome Atlas (TCGA) - a collaboration between NHGRI and the National Cancer Institute (NCI) - which generated over 2.5 petabytes of publically available genomic data used by the cancer research community to improve the prevention, …
Genetic Disorders
Klinefelter syndrome is a condition that occurs in men as a result of an extra X chromosome. The most common symptom is infertility.
… syndrome is associated with an increased risk for breast cancer, a rare tumor called extragonadal germ cell tumor, … Extra X Chromosome, Infertility, Gynecomastia, Breast Cancer, Extragonadal Germ Cell Tumor, Lung Disease, Varicose …
Outreach
15 examples of how genomics has and continues to transform our world in myriad ways.
… Complete Genome Sequence, Genomics Impact On Society, Cancer Genomics, Genomic Testing, Enhanced Forensics, Genome …
Diversity Center
Tuskegee University establishes the Carver Genomic Research Center.
… genomic research. CEC will help promote awareness of the cancer genomics, convene the Black Belt Community Advisory … in Urothelial Carcinoma Lead: Balu Karanam, Ph.D. Bladder cancer, the sixth most common cancer in the U.S., affects …
Research at NHGRI
Families Sharing Health Assessment and Risk Evaluation (SHARE) helps you and your family learn how your family health history affects your risk for diseases.
… Colorectal Cancer Breast Cancer Prostate Cancer Type 2 Diabetes Heart Disease How to Use the Families … to reduce risk of heart disease, diabetes, breast cancer, and colorectal cancer . BMC Public Health,  15: 1120, 2015. DOI: …
Clinical Research
A study for patients with unexpected genetic results
… unexpected genetic test results about their risk for cancer, heart disease, and other conditions after having … treated or prevented. Many of these results are related to cancer risk and heart conditions . If you think you have … or Spanish  Received a genetic testing result related to cancer risk or heart disease even though they were not …
FAQ
Questions and answers from the September 26, 2022, Multi-Omics for Health and Disease Consortium Pre-Application Webinar.
… both tumor and normal tissues from participants with cancer are strongly encouraged and will be prioritized for … Biosamples For the cancer DSS, can we propose just plasma collection and no … Collection of tumor samples from participants with cancer is encouraged but it is not a strict requirement. See …
Genetic Disorders
Crohn's disease is a chronic inflammatory disorder of the bowel, usually diagnosed in people between the ages of 20 - 30.
… in the affected area or surrounding tissues such as the bladder; tunnels around the anus and rectum called fistulas; …
Genomics and Medicine
Starting in 2019, the American Journal of Human Genetics has published an annual feature identifying ten key advances in applying genomic information to clinical care that were reported in the previous 12 months of published literature. The Genomic Medicine Working Group has authored these reviews, based on its broader effort to identify notable accomplishments in genomic medicine on a monthly basis. From this larger set of published accomplishments, the working group has continued to select ten papers annually to be highlighted as the most significant.
… with gene editing 7. Validation of a clinical breast cancer risk assessment tool for all ancestries 8. Broader … with rare diseases 9. Benefits for children with suspected cancer from routine whole-genome sequencing 10. Clinical … Population screening for hereditary breast and ovarian cancer is cost effective Australian implementation of …