Search Results
Policy Issues
NHGRI has created the IDE Greenhouse as an educational resource to help increase understanding of the regulation in the genomics context.
… The U.S. Food and Drug Administration (FDA) Investigational Device Exemption …
News Release
NIH awards more than $64 million to for a database of human cellular responses called the Library of Integrated Network-based Cellular Signatures or LINCS.
… you could figure out patterns of toxicity of potential new drug compounds by looking at cellular responses and finding … responses to drugs was more accurate than conventional drug-potency tests. This recognition may point the way toward … and diseased human cells. Dr. Sorger hopes that future drug developers will be able to perform computations on LINCS …
News Release
NHGRI will highlight rare disease research that benefits affected patients and provides insights into more common disorders on Rare Disease Day.
Fact Sheets
Genetics refers to the study of genes and their roles in inheritance. Genomics refers to the study of all of a person's genes (the genome).
… account a person's genetic information regarding specific drug receptors and how drugs are transported and metabolized … goal of pharmacogenetics is to create an individualized drug therapy that allows for the best choice and dose of drugs. One example is the breast cancer drug trastuzumab (Herceptin). This therapy works only for …
Fact Sheets
A biological pathway is a series of actions among molecules in a cell that leads to a certain product or a change in the cell.
… hope was based on the success of imatinib (Gleevec), a drug that was specifically designed to treat a blood cancer … in many CML patients. Unfortunately, the one-target, one-drug approach has not held up for most other types of cancer. … pathways and the genetic profiles of particular tumors, drug developers might be able to focus their attention on …
News Release
NHGRI researchers found that a protein in the immune system is particularly adaptable to mutations.
News Release
NHGRI researchers identified 59 genes or gene regions linked to canine athletics.
News Release
The U.S. National Institutes of Health (NIH) has long invested in basic genetics and genomics research, clinical trials, as well as translational medicine and social science studies, to advance our understanding of this widespread illness to help develop effective therapies.
… Today, the U.S. Food and Drug Administration (FDA) approved two gene therapies for the …
NEWS RELEASE
Final outcomes from the most comprehensive analysis to-date of humans and their microbiomes definitively link microbes and microbial activities with health problems.
File
… The Food and Drug Administration’s (FDA) Oversight and Regulation of …