Search Results
Policy Issues
Scientific institutions are developing recommendations to support the responsible use of human gene-editing research.
… In the United States and around the world, scientific institutions are developing … In light of recent advances in gene-editing research and technologies, the National Academies of Sciences, Engineering, and Medicine (NASEM) launched an initiative  in December …
Educational Resources
A polygenic trait is one whose phenotype is influenced by more than one gene.
… as height or skin color, that is influenced by two or more genes. Because multiple genes are involved, polygenic traits do not follow the … polygenic traits are also influenced by the environment and are called multifactorial. …
Genetic Disorders
Attention Deficit Hyperactivity Disorder (ADHD) is a neurological disorder that affects a person's ability to control their behavior and pay attention to tasks.
… that affects a person's ability to control their behavior and pay attention to tasks. … that are needed for tasks such as sustaining attention and regulating activity levels. … motor skills, social skills, control of emotions, and response to discipline are common. Sleep problems can …
Educational Resources
A physical map of a chromosome or a genome that shows the physical locations of genes and other DNA sequences of interest.
… or a genome that shows the physical locations of genes and other DNA sequences of interest. … of physical locations of landmarks or markers (such as genes, variants and other DNA sequences of interest) within a chromosome or … or a genome that shows the physical locations of genes and other DNA sequences of interest. …
Educational Resources
A locus is the specific physical location of a gene or other DNA sequence on a chromosome, like a genetic street address.
Fact Sheet
Your mental and physical health are deeply connected. Mental health is important for your overall health and quality of life.
… As a person living with sickle cell disease, you and your support systems make choices about your physical … while thinking about the impact on your mental health and psychological well-being.  These are some questions and actions you may want to take as you think about receiving …
Educational Resources
Mapping is the process of making a representative diagram cataloging the genes and other features of a chromosome and showing their relative locations.
… process of making a representative diagram cataloging the genes and other features of a chromosome and showing their relative locations. … Genetic Mapping, Recombinant DNA, Genes, Chromosome … the relative locations of landmarks or markers (such as genes, variants and other DNA sequences of interest) within a …
Educational Resources
A copy number variation (CNV) is when the number of copies of a particular gene varies from one individual to the next.
… about through duplications, deletions or other changes and can affect long stretches of DNA. Such regions may or may …
Genetic Disorders
Duchenne muscular dystrophy is a rapidly progressive form of muscular dystrophy caused by a mutation in the DMD gene.
… who have DMD have progressive loss of muscle function and weakness, which begins in the lower limbs. The DMD gene … The symptoms usually appear before age 6 and may appear as early as infancy. Typically, the first … symptom is delay of motor milestones, including sitting and standing independently. The mean age for walking in boys …
Research Funding
The centers define the state-of-the-art study designs and methods to find variants and genes underlying Mendelian disorders.
… Genomics (CMG) in 2011 with the charge to discover as many genes underlying human Mendelian disorders as possible. In … the CMGs will define the state-of-the-art study designs and methods to find the variants and genes underlying Mendelian disorders. … The discovery of the genes and genetic variants that underlie human Mendelian …