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Educational Resources
An anticodon is a trinucleotide sequence complementary to that of a corresponding codon in a messenger RNA (mRNA) sequence.
Educational Resources
A contig is a series of overlapping DNA sequences used to make a map that reconstructs the original DNA sequence of a chromosome or a region of a chromosome.
News Release
New grants totaling approximately $29.5 million will enable scientists to generate and maintain the most comprehensive reference sequence of the human genome.
… The funds are necessary for making advances in DNA sequencing technology and computational methods possible. As … (HGRP). “It has grown more and more important to have a high-quality, highly usable human genome reference sequence … additional diverse human genomes using state-of-the-art technologies to incorporate high-quality sequences that are …
Media Advisory
The National Institutes of Health (NIH) will host researchers from the Telomere-to-Telomere (T2T) consortium, who have now sequenced the remaining 8% of DNA that was unable to be sequenced by the Human Genome Project and has eluded researchers for nearly two decades.
… What: Virtual press conference to announce T2T consortium sequencing a complete human genome Moderator: Eric Green, …
Staff
Dr. Mullikin was the former director of the NIH Intramural Sequencing Center (NISC).
… to analyze large data sets generated by systematic DNA sequencing projects. A highly skilled computational … are in developing novel and efficient algorithms using high-performance compute clusters to reduce large data sets … change, which has now seen next-generation sequencing throughput increase 20-fold. This growth has complemented …
Staff
Dr. Gerard Bouffard directs the Bioinformatics Group at the NIH Intramural Sequencing Center (NISC).
… where he combined his interests in early genome sequencing of the Escherichia coli genome with the nascent … expedited gene discovery on this chromosome, and directed sequencing efforts in the early days of the Human Genome … exercise the capabilities of revolutionary DNA sequencing technologies and advanced information technologies. NISC …
The Genomics Landscape
In the April 7, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., highlights the Telomere-to-Telomere (T2T) consortium's publishing of a collection of papers that reported the first truly complete sequence of the human genome.
… took the practical approach of using the best-available technologies for sequencing DNA and pushing them to their absolute limits. In the end, it delivered a remarkably high-quality human genome sequence that was nearly complete, … p.m. ET for a live mini-conference entitled “ Nanopore Sequencing: From Genomes to Proteomes ” aimed at …
News Release
A team of NIH-funded researchers have generated the first complete chromosome sequences from non-human primates.
… has only become possible in recent years due to new DNA sequencing technologies and analysis methods. These chromosome sequences … High Resolution Image …
Research Funding
The $1,000 Genome Program was a coordinated effort to support the development of technologies to dramatically reduce the cost of DNA sequencing, a move aimed at broadening the applications of genomic information in medical research and health care.
… a coordinated effort to support the development of technologies to dramatically reduce the cost of DNA sequencing, a move aimed at broadening the applications of … Program, which was led by Dr. Jeffery Schloss , as the Sequencing Technology Development Program Director at NHGRI, …
The Genomics Landscape
In the May 2020 edition of The Genomics Landscape, NHGRI Director Eric Green details how NIH is ramping up research on COVID-19; NHGRI's expansion of its Genome Technology Program; and the the DiY Genome: Unlocking Life's Code exhibition toolkit.
… Some research groups are deploying their available DNA-sequencing and genotyping capabilities to perform COVID-19 … is designed to support both early innovation and advanced technologies, regardless of their stage in development, to … investigators developing novel synthetic nucleic acid technologies and a coordinating center, respectively. New …