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Staff
Dr. Adebowale Adeyemo is an associate investigator and deputy director of NHGRI's Center for Research on Genomics and Global Health.
… at NHGRI in 2016. Dr. Adeyemo works on the genomics of complex disease, focusing on cardiometabolic disorders and … obesity and diabetes, are non-communicable conditions of major public health and clinical significance. Dr. Adeyemo's … second leading cause of kidney disease in childhood and a major cause of end stage kidney disease requiring dialysis …
Educational Resources
A histone is a protein that provides structural support to a chromosome.
News Release
The U.S. Food and Drug Administration has approved the first treatment for progeria, a rare and fatal pediatric disease, characterized by dramatic, rapid aging beginning in childhood.
… Francis S. Collins, M.D., Ph.D., available to discuss this major advance for rare, fatal pediatric disease. … What The …
The Genomics Landscape
In the January 2020 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the newly developed polygenic risk scores webpage, which provides graphical and textual information about polygenic risk scores, describes polygenic traits, introduces how polygenic risk scores can be calculated, and explains how such scores can be interpreted.
… need for international research collaborations to tackle major challenges in genomic and precision medicine. It will … interdisciplinary program that will include both major research projects as well as core facilities that will facilitate use of the growing datasets emanating from major cohort studies (such as the UK Biobank and the All of …
Educational Resources
Transcription is the process of making an RNA copy of a gene sequence.
… protein information encoded in DNA. In humans and other complex organisms, mRNA moves from the cell nucleus to the …
The Genomics Landscape
In the January 5, 2023 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., talks about how artificial intelligence and machine learning are becoming omnipresent throughout NHGRI and in genomics.
… scholarly perspectives about multiple issues related to complex areas of social and behavioral genomics. All the … setting the stage for widespread adoption of AI to tackle complex biomedical challenges beyond human intuition. The … and healthcare research. Bridge2AI includes projects with major genomics components. Ten years ago, it was hard to …
For Teachers
Tools and resources for teaching the concepts of transcription and translation, two key steps in gene expression
… your students. Many times the unfamiliar vocabulary is the major stumbling block to student comprehension. This app/site … could be adapted for upper-level courses by including more complex problems and aspects of gene expression, such as the …
Educational Resources
Proteins are an important class of molecules found in all living cells.
… Amplification, Amino Acids, Gene … Proteins are large, complex molecules that play many important roles in the body. …
Fact Sheets
Deoxyribonucleic acid (DNA) is a molecule that contains the biological instructions that make each species unique.
… Besides the DNA located in the nucleus, humans and other complex organisms also have a small amount of DNA in cell … that can be used to produce proteins, which are the complex molecules that do most of the work in our bodies. … the amino acids to produce a specific protein. This is a major task because there are 20 types of amino acids, which …
Health
A polygenic risk score is one way by which people can learn what their risk of developing a disease is, based on the total number of genomics variants related to the disease.
… Each larger “V” represents a CFTR gene mutation. … Complex diseases occur as a result of many genomic variants, … not implicated in disease. Coronary artery disease is a complex disease. Researchers have found about 60 genomic … … Researchers identify genomic variants associated with complex diseases by comparing the genomes of individuals with …