Search Results
Policy Issues
Scientific institutions are developing recommendations to support the responsible use of human gene-editing research.
… and clinical research involving recombinant DNA (in which genes from different sources are combined). On June 21-22, … For instance: NHGRI's Embryonic Stem Cell and Transgenic Mouse Core uses CRISPR to generate laboratory mice with … researchers take advantage of this resource. The Knockout Mouse Project (KOMP) is an National Institutes of Health …
Educational Resources
Positional cloning is a laboratory technique used to locate the position of a disease-associated gene along the chromosome.
News Release
NIH will renew three awards totaling $73.2 million over five years to continue building the Clinical Genome (ClinGen) resource, an effort to collect and archive information about clinically relevant genes and genomic variants for use in precision medicine.
… collect and archive information about clinically relevant genes and genomic variants for use in precision medicine. The … lack of organized availability of information about which genes and genomic variants are relevant to human disease. … to fill that gap. The consortium works to identify which genes are associated with disease and which variants in those …
Fact Sheet
A variety of approaches target the blood stem cells to relieve or reduce your symptoms of sickle cell disease.
… , your stem cells are changed by altering part of your genes. Types of gene therapy include gene addition and gene … are present at the time of the gene therapy nor alter the genes that you pass on to your children. … your stem cells are replaced with new stem cells that have genes that do not code for sickle cell disease. These new …
Clinical Research
The CLINSEQ® Study seeks to learn about the role that your genes play in your health.
… The CLINSEQ® Study seeks to learn about the role that your genes play in your health. We do this by getting a DNA sample from you, sequencing most or all of your genes, and comparing that to what we know about your personal and family health histories. We look at genes related to a variety of conditions, including heart …
Educational Resources
The instructions in a gene that tell the cell how to make a specific protein.
… ACGT, Base Pairs, Genes, DNA, Double Helix, Adenine, Cytosine, Guanine, Thymine …
Educational Resources
Recessive Traits and Alleles is a quality found in the relationship between two versions of a gene.
Educational Resources
Duplication is a type of mutation that involves the production of one or more copies of a gene or region of a chromosome.
… Mutation, Chromosome, Genes, Evolution …
News Release
Using a recently developed DNA base-editing technique, researchers correct accelerating aging disorder.
… DNA-editing method shows promise to treat mouse model of progeria …