Search Results
The Genomics Landscape
In the October 2024 issue of The Genomics Landscape, NHGRI Director Eric Green welcomes James Thomas as the new director for NIH Intramural Sequencing Center (NISC).
… from the University of California, San Diego, introduced a new tool called prancSTR, which is designed to help … contributes to disease and inform the development of new genetic testing methods.  This research was funded by …  NHGRI recently appointed James Thomas, Ph.D. , as the new director of the NIH Intramural Sequencing Center (NISC) …
Media Availability
Researchers have used a new combination of microfluidics and genomics to fish out a specific gut bacterium from the sea of microbes in the human microbiome.
… The new method has broad applications for isolating and studying … New approach may improve study of hard-to-grow, … Researchers have used a new combination of microfluidics and genomics to fish out a … Researchers have used a new combination of microfluidics and genomics to fish out a …
Educational Resources
In genomic imprinting the ability of a gene to be expressed depends upon the sex of the parent who passed on the gene.
… In genomic imprinting the ability of a gene to be expressed depends upon the sex of the parent who passed on the gene. … DNA Sequence, Genes, Family Health History, Genealogy, Gene Expression … imprinting is the process by which only one copy of a gene in an individual (either from their mother or their …
Research at NHGRI
The Social and Behavioral Research Branch conducts research to apply genomic discoveries to improve health and clinical care.
… with the four themes below. The social context of genomic discovery We approach research with a social genomics lens. … so, we consider the effect of adverse social factors on gene expression in population groups that are … explore these connections. Clinical translation of genomic discovery We approach clinical translation through several …
Educational Resources
A genotype is an individual's collection of genes.
… BB, Bb, bb could be used to represent a given variant in a gene. Genotypes can also be represented by the actual DNA …
Fact Sheets
Genetics refers to the study of genes and their roles in inheritance. Genomics refers to the study of all of a person's genes (the genome).
… factors than by individual genes. Genomics is offering new possibilities for therapies and treatments for some complex diseases, as well as new diagnostic methods. … Understanding more about diseases caused by a single gene (using genetics) and complex diseases caused by multiple …
News Release
Over the last 20 years, three families have been unknowingly linked to one another by an unknown illness. Researchers at the National Human Genome Research Institute (NHGRI) and other organizations have now identified the cause of the illness, a new disease called CRIA syndrome. The results of their work were published on Dec. 11 in the journal Nature.
… Mutations in the RIPK1 gene responsible for CRIA syndrome Over the last 20 years, … have now identified the cause of the illness, a new disease called CRIA syndrome. The results were published … elsewhere, it was clear that they were onto something new. “It was as if lightning had struck three times in the …
News Release
Researchers have now identified and catalogued more species - nearly 200 new bacteria and thousands of viruses - that reside on the human skin than has ever been possible, largely due to advances in bioinformatics and laboratory techniques.
… Study identifies nearly 200 new bacteria and thousands of viruses residing on skin, far … the most abundant on human skin. The results appear in a new catalog, the Skin Microbial Genome Collection (SMGC), … in the collaborative study. According to researchers, the new catalog is remarkable in its breadth, bringing to light …
For Teachers
The genetic timeline lesson plan gives students an historical perspective of the discoveries that led to our present understanding of the human genome.
… objectives: Describe how scientific "facts" change with new discoveries. Give examples of the small steps toward … a change in scientific thinking with the collection of new knowledge. Describe the scientific process of using supporting evidence from one discovery to verify findings of another. Relate the …
Culture
Work with a talented team, including world-class scientists at NHGRI. Share genomics and its discoveries with the community and the world.
… build you career and help bring the fruits of genomic discovery to people's lives. … have changed the way researchers everywhere make new breakthroughs. We also study the important interface … of genomic advances can be either incredible or pose new challenges. Together we figure out how to consider these …