Search Results
Genomics and Medicine
The NHGRI Genomic Medicine Working Group has compiled a list of interesting advances.
… Genomic Medicine Working Group  (GMWG) compiles a list of interesting advances and helpful educational resources in … Milestones In Medicine, Clinical Implementation Of Genomics, Pharmacogenomics, Oncology Sequencing, … Group has compiled a list of interesting advances. … Genomics and Medicine …
Educational Resources
Population genomics is the application of genomic technologies to understand populations of organisms.
… Population Genomics … Population genomics is the application of genomic technologies to understand populations of organisms. … Gene, Genome, Genetic Variation, Allele, Founder Effect, …
Research at NHGRI
The NHGRI Cancer Genetics and Comparative Genomics Branch identifies and study genes that contribute to cancer susceptibility and progression.
… The Cancer Genetics and Comparative Genomics Branch seeks to identify and study genes that … to cancer susceptibility syndromes and to the development of various aggressive cancers, including prostate, … with both population scientists and clinicians to define gene profiles that offer predictability in terms of cancer …
Policy Issues
Genome editing is a method that lets scientists change the DNA of many organisms, including plants, bacteria, and animals.
… editing is a method that lets scientists change the DNA of many organisms, including plants, bacteria, and animals. … diseases that affect humans. They edit the genomes of animals, like mice and zebrafish, because animals have … about 85 percent of their genes! By changing a single gene or multiple genes in a mouse, scientists can observe how …
The Genomics Landscape
In the October 1, 2020 edition of The Genomics Landscape, Dr. Eric Green reflects on the last 30 years since the launch of the Human Genome Project.
… then a postdoctoral research fellow in the laboratory of genomics pioneer Maynard Olson at Washington University … a set of studies describing how DNA variation can alter gene expression. The group of papers, published in Science …
Fact Sheets
Genome-wide association studies involve scanning markers across the genomes of many people to find genetic variations associated with a particular disease​.
… studies involve scanning markers across the genomes of many people to find genetic variations associated with a … involves rapidly scanning markers across the complete sets of DNA, or genomes, of many people to find genetic variations … form of blindness is associated with variation in the gene for complement factor H, which produces a protein …
Talking Glossary
Methylation is a chemical modification of DNA and other molecules that may be retained as cells divide to make more cells. regulating the production of proteins that the gene encodes.
… Methylation … Methylation is a chemical modification of DNA and other molecules that may be retained as cells … make more cells. … Methylation is a chemical modification of DNA and other molecules that may be retained as cells … make more cells. When found in DNA, methylation can alter gene expression. In this process, chemical tags called methyl …
The Genomics Landscape
In the July 2020 edition of The Genomics Landscape, NHGRI Director Eric Green recalls the White House event announcing the draft human genome sequence.
… Eric Green, M.D., Ph.D. … As is likely the case for many of your organizations, NHGRI and NIH are starting to bring … past few months, NHGRI staff will continue pursuing our genomics-driven mission, whether working remotely from home … one that covered about 99 percent of the genome's gene-containing regions and had an accuracy of 99.99 percent. …
Educational Resources
A physical map of a chromosome or a genome that shows the physical locations of genes and other DNA sequences of interest.
… Physical Map … A physical map of a chromosome or a genome that shows the physical locations … genes and other DNA sequences of interest. … Chromosome, Gene, Deoxyribonucleic Acid (DNA), Positional Cloning … A physical map, as related to genomics, is a graphical representation of physical locations …
The Genomics Landscape
In the March 2020 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the newly appointed Dr. Chris Gunter's role as Senior Advisor for Genomics Engagement as well as the 30 oral histories to celebrate the 30th anniversary of the launch of the Human Genome Project.
… The first such AGBT meeting was held in 2000, when most of the attendees were – in one way or another – busily … is gratifying to reflect on the amazing metamorphosis of genomics over the last two decades, especially with respect … link higher maternal blood pressure to placental gene changes Genetic profile may predict chance of type 2 …