Search Results
Genomics and Medicine
The NHGRI Genomic Medicine Working Group has compiled a list of interesting advances.
… Genomic Medicine Working Group  (GMWG) compiles a list of interesting advances and helpful educational resources in … about the selection criteria and categories, see the list of categories and their definitions . … NHGRI Genomic Medicine Working Group has compiled a list of interesting advances. …
Research at NHGRI
The NHGRI Cancer Genetics and Comparative Genomics Branch identifies and study genes that contribute to cancer susceptibility and progression.
… The Cancer Genetics and Comparative Genomics Branch seeks to identify and study genes that … to cancer susceptibility syndromes and to the development of various aggressive cancers, including prostate, … variation and cancer progression and pursue the discovery of both inherited and somatic variants that lead, …
Educational Resources
A genotype is an individual's collection of genes.
… A genotype is an individual's collection of genes. … A genotype is a scoring of the type of variant present at a given location (i.e., a locus) in the … BB, Bb, bb could be used to represent a given variant in a gene. Genotypes can also be represented by the actual DNA …
The Genomics Landscape
In the October 1, 2020 edition of The Genomics Landscape, Dr. Eric Green reflects on the last 30 years since the launch of the Human Genome Project.
… then a postdoctoral research fellow in the laboratory of genomics pioneer Maynard Olson at Washington University … with the Human Genome Project successfully completed and genomics maturing into a well-respected discipline. I am so … and accomplishments from the institute and the field of genomics. …
Policy Issues
Genome editing is a method that lets scientists change the DNA of many organisms, including plants, bacteria, and animals.
… editing is a method that lets scientists change the DNA of many organisms, including plants, bacteria, and animals. … diseases that affect humans. They edit the genomes of animals, like mice and zebrafish, because animals have … about 85 percent of their genes! By changing a single gene or multiple genes in a mouse, scientists can observe how …
Educational Resources
Population genomics is the application of genomic technologies to understand populations of organisms.
… Population Genomics … Population genomics is the application of genomic technologies to understand populations of organisms. … Gene, Genome, Genetic Variation, Allele, Founder Effect, … Population genomics is the large-scale application of genomic technologies to study populations of individuals. …
Fact Sheets
Genome-wide association studies involve scanning markers across the genomes of many people to find genetic variations associated with a particular disease​.
… studies involve scanning markers across the genomes of many people to find genetic variations associated with a … involves rapidly scanning markers across the complete sets of DNA, or genomes, of many people to find genetic variations associated with a … With the completion of the Human Genome Project in 2003 and the International …
News Release
The zebrafish is a powerhouse tool that helps researchers better understand the genes that are implicated in disease.
… In the basement of a three-story brick building on the main campus of the National Institutes of Health live nearly half a million organisms that breathe … But this wee creature is making big waves in the sea of genomics research. The zebrafish is a powerhouse tool that …
About Genomics
A introduction to basic concepts in genomics to help you understand your genome, how it works, and how it impacts your health.
… disorder. The results help to determine a person’s risk of developing the specific disorder being tested for. These … or rule out a suspected genetic disorder. The results of a diagnostic test may help you make choices about how to … identify biological family members, suspects, and victims of crimes and disasters. …
The Genomics Landscape
In the July 2020 edition of The Genomics Landscape, NHGRI Director Eric Green recalls the White House event announcing the draft human genome sequence.
… As is likely the case for many of your organizations, NHGRI and NIH are starting to bring … past few months, NHGRI staff will continue pursuing our genomics-driven mission, whether working remotely from home … findings of sexual harassment. Last month’s issue of The Genomics Landscape featured NHGRI efforts to develop a plan …