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News Release
Charles Rotimi, Ph.D., was awarded the Academy Medal for Distinguished Contributions in Biomedical Science by the New York Academy of Medicine. This honor, established in 1929, recognizes investigators with sustained and impactful accomplishments in biomedical research and an interest in translating these findings to advance human health.
… data from admixed groups and individuals of African ancestry has enhanced approaches to finding genomic variants for complex traits and uncovered ways in which ancestry can influence genetic findings. Over the last …
News Release
NIH will fund grants totaling $38 million over five years to develop methods that will improve the way that polygenic risk scores can be used to predict disease in diverse communities.
… which were developed using data from mostly European ancestry populations, are not effective when used in diverse …
Staff
Dr. Daniel Shriner is a researcher in NHGRI's Center for Research on Genomics and Global Health.
… association for renal traits among participants of African ancestry reveals new loci for renal function. PLoS Genet ., … Shriner , D ., Adeyemo, A., and Rotimi, C. N. 2011. Joint ancestry and association testing in admixed individuals. PLoS … and Rotimi, C. N. 2012. Variation in APOL1 contributes to ancestry-level differences in HDLc-kidney function …
Event
On October 25-29, 2022, the National Human Genome Research Institute (NHGRI) will participate in the ASHG Annual Meeting - the world's largest human genetics and genomics meeting and exposition.
… Traits Quantification of race, ethnicity, and genetic ancestry disparities in anti-hypertensive drug efficacy in … Research Quantification of race, ethnicity, and genetic ancestry disparities in anti-hypertensive drug efficacy in … p.m. Statistical Genetics and Genetic Epidemiology Local Ancestry at the MHC region id asscociated with disease …
Genomics and Medicine
Starting in 2019, the American Journal of Human Genetics has published an annual feature identifying ten key advances in applying genomic information to clinical care that were reported in the previous 12 months of published literature. The Genomic Medicine Working Group has authored these reviews, based on its broader effort to identify notable accomplishments in genomic medicine on a monthly basis. From this larger set of published accomplishments, the working group has continued to select ten papers annually to be highlighted as the most significant.
The Genomics Landscape
In the February 2, 2023 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., talks about the new NIH Data Management and Sharing (DMS) Policy and how it emphasizes the importance of good data management practices.
… 2022. PMC9793425  One method for studying the ancestry of a human population involves the use of DNA from …
Event
The Inter-Society Coordinating Committee for Practitioner Education in Genomics (ISCC-PEG) will hold its 11th annual meeting online on February 16, 2022.
… L, Wilbur WJ, Lu Z, Brody LC, Bonham VL. Evolving use of ancestry, ethnicity, and race in genetics research-A survey …
Staff
Dr. Elisabeth F. Heuston is a molecular biology and bioinformatics Staff Scientist with the Center for Research on Genomics and Global Health (CRGGH).
… of complex traits among populations of African ancestry. Using her multidisciplinary background, she aims to …
Genetic Disorders
Gaucher disease is an autosomal recessive inherited disorder of metabolism where a type of fat (lipid) called glucocerebroside cannot be adequately degraded.
… frequently among individuals who are of Ashkenazi Jewish ancestry. Type 1 Gaucher disease is present 1 in 500 to 1 in 1000 people of Ashkenazi Jewish ancestry, and approximately 1 in 14 Ashkenazi Jews is a …
Healthcare Provider Genomics Education Resource
An FAQ designed to help healthcare professionals understand the diverse landscape of direct-to-consumer (DTC) genetic testing and the benefits and limitations of these tests.
… information about their genetic information (generally ancestry, some health traits and health risks) from a saliva … the support of a qualified healthcare professional.  For ancestry results, DTC-GT may reveal a genetic relationship to … do not cover all ethnic populations equally; therefore ancestry results for underrepresented minority populations …