Search Results
Clinical Research
The CLINSEQ® Study seeks to learn about the role that your genes play in your health.
… by getting a DNA sample from you, sequencing most or all of your genes, and comparing that to what we know about your … health histories. We look at genes related to a variety of conditions, including heart disease, breast cancer, and hearing loss. … we still need more volunteers for the study. Each member of the study has a clinical visit and tests to look at heart …
Event
On November 16-17, 2023, the National Human Genome Institute will co-sponsor a workshop, Advances in the Genetic Architecture of Complex Human Traits, to take a historically grounded and forward-looking approach towards dissecting the genetic architecture of complex traits in humans.
… optical methods allow us to profile the molecular features of cells at scale. What’s needed, technically or … and traits? What does this mean for understanding human biology as universal and for the generation of other genomic … of biological organization? Emerging data from cancer biology, as well as immunology, implicate regulation of …
Explainer
Appropriate use of population descriptors in research is a critical scientific issue that is important for advancing genomic science and improving healthcare across human populations.
… The Big Picture Appropriate use of population descriptors in research is a critical … important given the ethical, legal and social implications of their historical and current use.  This explainer … ancestry — which are often used to distinguish groups of people participating in research and to inform some …
The Genomics Landscape
In the December 2018 edition of The Genomics Landscape, NHGRI Director Eric Green recaps progress from NHGRI strategic planning process events in 2018.
… As signaled by the rapid arrival of cold weather and the seemingly overnight arrival of holiday-themed daily life, the year 2018 is rapidly coming … process is in full swing and being conducted on top of our otherwise frenetic day jobs! That process will prove …
Jobs at NHGRI
Funded postdoctoral positions are available in the laboratory of Dr. Shawn Burgess, within NHGRI's Translational and Functional Genomics Branch.
… postdoctoral positions are available in the laboratory of Shawn Burgess, Ph.D., within the Translational and Functional Genomics Branch of the National Human Genome Research Institute (NHGRI) at the National Institutes of Health (NIH). … The focus of the Burgess lab is on the genetics and functional genomics …
Media Availability
TCGA researchers have found that chromophobe renal cell carcinoma stems partly from gene alterations in the mitochondria, the cell's energy supplier.
… The Cancer Genome Atlas (TCGA) Network have made a number of new findings about the biology and development of a rare form of kidney cancer. … cancers. In the study - the most extensive genomic view of ChRCC to date - investigators led by Chad Creighton, … families, through research into prevention and cancer biology, the development of new interventions, and the …
The Genomics Landscape
In the March 3, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., highlights the new fact sheets produced by the institute's Communications and Public Liaison Branch.
… In the January issue of The Genomics Landscape , I reported that Francis Collins … Institute did not even last three months! In the middle of February, Francis agreed to serve as the Acting Science Advisor to President Biden and Acting Co-Chair of the President’s Council of Advisors on Science and …
Genetic Disorders
Neurofibromatosis is a genetic neurological disorder that can affect the brain, spinal cord, nerves and skin.
… known as von Recklinghausen's NF, is the more common of the types. It occurs in approximately 1 in 4,000 births. … occurs less frequently- 1 in 40,000 births. Occurrences of NF1 and NF2 are present among all racial groups and affect … to developmental abnormalities and/or increased chances of having learning disabilities. Other forms of NF, where the …
Media Availability
Researchers have created a promising new method to accurately and more comprehensively analyze and interpret DNA sequence information from cancer patients.
… (NHGRI), and the National Cancer Institute, both part of the National Institutes of Health, in addition to other organizations. Investigators … families, through research into prevention and cancer biology, the development of new interventions, and the …
News Release
Researchers are trying to understand a process whose rules are constantly being written and rewritten by cancer's rogue cells: who will more likely relapse.
… For a patient with cancer, two of the most important words in the oncologist's lexicon begin … some patients will hear the word relapse - a return of the cancer and its symptoms. These words necessarily lead … while others see their cancer return? To get a better idea of who will be more likely to relapse, researchers are trying …