Search Results
Research Funding
The following are research areas of interest that have been identified by the participating NIH institutes, centers, and offices (ICOs) on the investigator-initiated ELSI Research Grants (R01, R21, R03). Program Officer(s) contact information is also included for each ICO.
… and sheds light on influential personal and environmental factors (e.g., experiences with genomics, family traditions, … disease, and other traits relative to other contributing factors. Includes how beliefs about the deterministic or … systems. It includes a focus on the internal and external factors impacting their actions and the corresponding impact …
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… ‐01A1 R01 TIMP, WINSTON Nanopore based profiling of epigenetic state 784,452 HG009187 ‐01A1 R21 BESTOR, TIMOTHY H … amplification 223,465 HG009578 -01 R43 ALDEN, JONATHAN Epigenetic fingerprinting of label -free DNA using a soliT …
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… GMXV - Considering the factors involved in calculating the “number needed” in …
Event
A 10-part seminar series in 2021 that focuses on the “Bold Predictions for Human Genomics by 2030” that are described in NHGRI’s “Strategic Vision for Improving Human Health at the Forefront of Genomics.”
… p.m. ET Bold Prediction #3: The general features of the epigenetic landscape and transcriptional output will be …
Educational Resources
Congenital conditions are those present from birth.
… or at birth, or they may be due to a combination of these factors. …
Educational Resources
A promoter is a sequence of DNA needed to turn a gene on or off.
… proteins (such as RNA polymerase and transcription factors) bind to initiate transcription of that gene. The …
News Release
Mothers may be able to reduce guilt over their children's inherited obesity guilt by being more careful in the future about their children's diet.
… providers who discuss genomics and behavioral risk factors with overweight mothers may make those mothers feel … mechanisms are far from understood, and the genetic risk factors are complex. They include gene-gene interactions, … that people may not realize the extent to which genetic factors could influence metabolism, as well as the behavioral …
FAQ
On November 8-9, 2023, NHGRI sponsored its 15th Genomic Medicine meeting, Genomic Medicine XV: Genomics and Population Screening, in Bethesda MD. The following questions were answered during the meeting.
… considering the scores in the context of non-genetic risk factors as a part of genetically informed risk assessment, … or background genetic ancestry, screening based on these factors will inevitably miss some persons at risk. Ideally, … and even control BP better for those with genetic risk factors for CKD, how do we address disparities in transplant …
For Patients and Families
A rare disease is generally considered to be a disease that affects fewer than 200,000 people in the United States at any given time.
… genetics are just one piece of the puzzle. Environmental factors, such as diet, smoking, or exposure to chemicals, also can play a role in rare diseases. Such factors may directly cause disease, or interact with genetic factors to cause or increase the severity of disease. …
Clinical Research
In the late 90’s and early 2000’s, scientists at the NIH highlighted an increased incidence of Parkinson disease among patients with GD and their families.