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Educational Resources
A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli).
… A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli). … Cloning, Bacteria, Bioengineering, DNA Sequencing, Base Pair, Chromosomes … A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells …
Educational Resources
Ribonucleic acid (RNA) is a molecule similar to DNA. Unlike DNA, RNA is single-stranded.
… Ribonucleic acid (RNA) is a molecule similar to DNA. Unlike DNA, RNA is single-stranded. … Cell, Genetic Code, Deoxyribonucleic Acid (DNA), Protein, Uracil, Adenine, Cytosine, Guanine, Messenger … in all living cells that has structural similarities to DNA. Unlike DNA, however, RNA is most often single-stranded. …
Staff
Dr. Paul Liu is a senior investigator in NHGRI's Translational and Functional Genomics Branch.
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… (CBFb and RUNX1, respectively) that form a dimer for DNA binding and gene expression regulation, are frequent … Current and future efforts in Dr. Liu's lab include more functional studies of CBFβ-SMMHC with novel transgenic mouse … in the zebrafish, this finding demonstrated significant functional conservation between mammalian and zebrafish …
Educational Resources
Antisense is the non-coding DNA strand of a gene.
… Antisense is the non-coding DNA strand of a gene. … Non-coding DNA, Messenger RNA, Protein Synthesis … Antisense is the non-coding DNA strand of a gene. In a cell, antisense DNA serves as the template for producing messenger RNA … Antisense is the non-coding DNA strand of a gene. …
Educational Resources
A mutagen is a chemical or physical phenomenon, such as ionizing radiation, that promotes errors in DNA replication.
… such as ionizing radiation, that promotes errors in DNA replication. … Mutagen, DNA Mutation, DNA Replication, Cancer … chemical or physical agent capable of inducing changes in DNA called mutations. Examples of mutagens include tobacco … variety of chemicals. Exposure to a mutagen can produce DNA mutations that cause or contribute to certain diseases. …
Educational Resources
Chromatin is a substance within a chromosome consisting of DNA and protein.
… Chromatin is a substance within a chromosome consisting of DNA and protein. … Chromosome, Histones, Gene Expression, DNA … Chromatin refers to a mixture of DNA and proteins that form the chromosomes found in the cells … — namely, histones — package the massive amount of DNA in a genome into a highly compact form that can fit in …
Educational Resources
Shotgun sequencing is a laboratory technique for determining the DNA sequence of an organism's genome.
… sequencing is a laboratory technique for determining the DNA sequence of an organism's genome. … Deoxyribonucleic Acid (DNA), DNA Sequencing, Genome, Human Genome Project … sequencing is a laboratory technique for determining the DNA sequence of an organism’s genome. The method involves …
Event
NHGRI workshop seeking scientific perspectives for relating genomic variation to human phenotype.
… NHGRI Staff 8:15 - 9:00 a.m. Current State of the Art: Functional Data, Analysis and Interpretation Hugo Bellen Lea … capabilities do we need to generate and make use of functional data? What is needed to overcome barriers to … and characterization of all genes and regulatory elements Co-Chairs: Kelly Frazer Wendy Chung Breakout 5 ( …
The Genomics Landscape
In the July 2021 issue of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., reflects on the legacy the LINCS program leaves as it has completed its goal of creating a large-scale, systematically generated molecular and cellular dataset.
Educational Resources
A plasmid is a small, often circular DNA molecule found in bacteria and other cells.
… A plasmid is a small, often circular DNA molecule found in bacteria and other cells. … Bacteria, Chromosome, Deoxyribonucleic Acid (DNA), Gene, Cloning, DNA Sequencing, Genetic Engineering Recombinant DNA (rDNA) … A plasmid is a small circular DNA molecule found in bacteria and some other microscopic …