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The Genomics Landscape
In the October 6, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., celebrates the 25th anniversary of the NIH Intramural Sequencing Center (NISC). a well-respected and highly used large-scale DNA sequencing center that exemplifies the evolution of the field of genomics and the ever-increasing abilities to produce prodigious amounts of genomic data.
… Sequencing Project and NHGRI’s Encyclopedia of DNA Elements (ENCODE) Project . In the case of ENCODE, NISC’s … datasets that provided new insights about non-coding functional elements in the human genome. When significant interest in …
Fact Sheets
Comparative genomics is a field of biological research in which researchers compare the complete genome sequences of different species.
… initial catalog of yeast genes and to predict a new set of functional elements that play a role in regulating genome activity, not … NHGRI programs such as ENCODE (Encyclopedia of DNA Elements) and modENCODE (model organism Encyclopedia of DNA Elements) have compared and contrasted the inner workings of …
Research Funding
A list of current and previous Centers of Excellence in Genomic Science (CEGS) grant awards.
… systems; and to develop tools that leverage multiplex functional data to improve the prediction of disease risk. … and gene expression as well as interrogation of the functional consequences of sequence variants at a scale and … RNAs, long noncoding RNA and a host of other regulatory elements such as enhancers and insulator regions. Critically, …
The Genomics Landscape
In the July 2024 issue of The Genomics Landscape, NHGRI Director Eric Green welcomes the inaugural class of the ASHG-NHGRI Genomics and Public Service Fellowship Program.
… and breadth of the scientific, clinical, and societal elements of human genetics and genomics, as well as to …
Staff
Dr. Elisabeth F. Heuston is a molecular biology and bioinformatics Staff Scientist with the Center for Research on Genomics and Global Health (CRGGH).
… of mentor Dr. Robert J. Arceci, Dr. Heuston used in vitro functional assays and in vivo rodent models to identify … aims to create a catalogue of functionally-defined genomic elements that influence the pathophysiology of …
The Genomics Landscape
In the October 2021 issue of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., introduces us to new scientific director Charles Rotimi, Ph.D., his background and prior accomplishments.
… map of the functions of regulatory and non-regulatory gene elements. The IGVF consortium includes five components: functional characterization centers, regulatory network …
News Release
NHGRI researchers identified 59 genes or gene regions linked to canine athletics.
Research Funding
The Genomics of Gene Regulation project develops methods to construct predictive, accurate gene regulatory network models using genomic data​​.
… expression, as well as surrogate markers of regulatory elements, in different cell fates or cell states. They use the gene expression and functional element data to construct gene regulatory network … methods with catalogs of genomic data to understand what elements are controlling what genes, in what cell types. The …
News Release
NHGRI hosted two Pathway to Independance awardees and supported 18 additional investigators at institutions nationwide.
… of Michigan, Ann Arbor, Global Discovery and Validation of Functional Regulatory Elements James Bentley Brown, Ph.D., University of … National Laboratory, Berkeley, Nonparametric Methods for Functional and Translational Genomics Christopher Cassa, …
Staff
Kris Wetterstrand is the program operations lead in the NIH Division of Extramural Operatons.
… Genome Project, the ENCODE Project, an effort to identify functional DNA elements in the human genome, and the Human Microbiome …