Search Results
Research at NHGRI
The NHGRI Cancer Genetics and Comparative Genomics Branch identifies and study genes that contribute to cancer susceptibility and progression.
… and Comparative Genomics Branch seeks to identify and study genes that contribute to cancer susceptibility and … lung, head and neck, and gastric cancers. They also study the relationship between genetic variation and cancer … implement new technologies and bioinformatics tools for genome analysis that are integral to this discovery pipeline. …
Research at NHGRI
The Medical Genetics Branch studies inherited disorders of metabolism and of human development.
… molecular, and cell biological levels involve the direct study of human subjects as well as the development and use of …
News Release
Research points to the effects of nutrients in how DNA mutates in the mitochondria.
… Brody, Ph.D., a senior scientist at the National Human Genome Research Institute (NHGRI), part of the National … and three Es. These impacts have been studied in the human genome. However, Drs. Brody and Parle-McDermott aimed to look … researchers then examined data from the Framingham Heart Study , a long-term research effort conducted in the U.S. …
Genomics and Medicine
The categories for the notable accomplishments of research are defined as research that uses genomics to generate or study.
… (below) as research that uses genomics to generate or study.  Category Information Content Genomic Medicine … are defined as research that uses genomics to generate or study. … are defined as research that uses genomics to generate or study. …
Fact Sheet
Several regulations and policies stipulate the information that must be given to research participants prior to their enrolling in a study.
… informed choice about whether to participate in a research study.  In the United States, the requirements for obtaining … taken by the U.S. Government during the Tuskegee Syphilis Study from 1932-1972 without the consent of the men involved in the study led to the creation of National Commission for the …
Research at NHGRI
The Metabolic, Cardiovascular and Inflammatory Disease Genomics Branch studies the genomic and social determinants of complex diseases.
Research Funding
The centers define the state-of-the-art study designs and methods to find variants and genes underlying Mendelian disorders.
… The National Human Genome Research Institute funded the Centers for Mendelian … In doing so, the CMGs will define the state-of-the-art study designs and methods to find the variants and genes … of the genetic basis of Mendelian disorders using genome-wide approaches, which are more rapid and …
News Release
NIH-led study finds genetic markers that explain up to 12% of the differences between two people’s blood pressure.
… NIH-led study finds genetic markers that explain up to 12% of the … have discovered over 100 new regions of the human genome, also known as genomic loci , that appear to … the researchers combined four large datasets from genome-wide association studies of blood pressure and hypertension. …
Media Availability
The Cancer Genome Atlas identified molecular subtypes to help clinicians determine which tumors are more aggressive and which will respond to treatment.
… WHAT: Investigators with The Cancer Genome Atlas (TCGA) Research Network identified new molecular … cancer responds differently to particular therapies. The study also showed that BRAF -driven tumors have a broader … by the National Cancer Institute and the National Human Genome Research Institute, both parts of the National …
AnVIL
The Data Use Oversight System (DUOS) is a semi-automated study registration and DAR management service informed by the GA4GH DUO standard, which enables the secondary use of human genomics and other controlled-access data in compliance with the informed consent of a study’s participants.
… manner that is consistent with the informed consent of the study’s participants. The growing demand for … D ata U se O versight S ystem ( DUOS ) is a semi-automated study registration and DAR management service informed by the … data in compliance with the informed consent of a study’s participants. Four NIH DACs have tested DUOS to …