Search Results
Research at NHGRI
The Medical Genetics Branch studies inherited disorders of metabolism and of human development.
News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… have not been confirmed by knocking them out in animal models and seeing what happens. "This is a way to do that on …
Research at NHGRI
The Metabolic Medicine Branch houses clinical and laboratory research programs that focus on the development of new therapies for patients with genetic disorders.
… including stem cell, organoid, zebrafish and mouse models to mimic aspects of the conditions in the laboratory. … caused by mitochondrial dysfunction and create mouse models to test novel small molecules to treat genetic …
Staff
Dr. Ellen Sidransky is a pediatrician and clinical geneticist in the Medical Genetics Branch at the National Human Genome Research Institute.
… analyses, as well as studies utilizing cells, animal models and human brain samples. With funding from the NIH … dopaminergic neurons, astrocytes and macrophages. Mouse models of Gaucher disease have been crossed with Parkinson disease models, demonstrating that deficient glucocerebrosidase …
News Release
NIH has awarded grants of more than $28 million aimed at deciphering the language of how and when genes are turned on and off.
Research Funding
A list of current and previous Centers of Excellence in Genomic Science (CEGS) grant awards.
… personalized medicine and aggressively humanized mouse models. Specifically, we will (i) enhance our Design – Build … in the production of extensively humanized animal models called Genomically Rewritten and Tailored Genetically Engineered Mouse Models (GREAT-GEMMs), an element of our program worthy of …
News Release
NHGRI researchers will present four platform talks and 55 posters to highlight the institute's diverse portfolio at the 65th annual meeting of ASHG.
… Session #72: Inborn Errors of Metabolism: Novel Disorders, Models, and Observations; Hilton Baltimore Hotel, Holiday … variable selection method for identifying complex genetic models associated with human traits. (Statistical Genetics … GBA1 mutations and synucleinopathies with in vivo mouse models. (Psychiatric Genetics, Neurogenetics and …
Intramural Training Office
Three-minute talk (TmT) presentation videos from previous years dating back to 2015.
Research Funding
NHGRI's programs and projects support research in one of six domains to advance the field of genomics and improve human health.
Research at NHGRI
The NHGRI Division of Intramural Research aims to advance the frontiers of genetics and genomics.
… mission. Finally, studies of development biology, animal models, and basic molecular mechanisms are critical for …