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News Release
New grants totaling approximately $29.5 million will enable scientists to generate and maintain the most comprehensive reference sequence of the human genome.
… human genome is becoming obsolete. The funds are necessary for making advances in DNA sequencing technology and computational methods possible. As … the new program. NHGRI has awarded $2.5 million per year for five years to Washington University in St. Louis (WashU), …
Educational Resources
A stop codon is a trinucleotide sequence within a messenger RNA (mRNA) molecule that signals a halt to protein synthesis.
… Amino Acids, Cell, Codon, Deoxyribonucleic Acid (DNA), Gene Environment Interaction, Genetic Code, …
The Genomics Landscape
In the April 7, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., highlights the Telomere-to-Telomere (T2T) consortium's publishing of a collection of papers that reported the first truly complete sequence of the human genome.
… The beginning of spring brings some good budgetary news for NIH and NHGRI. On March 11, the U.S. Congress passed a … Year 2022 federal budget, which provides ~$45 billion for NIH (an increase of $2.03 billion). NHGRI’s budget is … Office of Communications (or “the OC”). Part of the reason for this renaming was to provide name symmetry for the three …
Educational Resources
A physical map of a chromosome or a genome that shows the physical locations of genes and other DNA sequences of interest.
… Chromosome, Gene, Deoxyribonucleic Acid (DNA), Positional Cloning … are also valuable in providing an organizational framework for generating complete sequences of genomes. …
Staff
Dr. Mullikin was the former director of the NIH Intramural Sequencing Center (NISC).
… greatly sped up the process of SNP discovery, first for The SNP Consortium Project and later in the International … to analyze large data sets generated by systematic DNA sequencing projects. A highly skilled computational … developing data analysis methods specifically tailored for each class of project. …
Educational Resources
Polymerase chain reaction (PCR) is a laboratory technique used to amplify DNA sequences.
… Deoxyribonucleic Acid (DNA), DNA Replication, Enzyme, Genome, Primer … chain reaction (abbreviated PCR) is a laboratory technique for rapidly producing (amplifying) millions to billions of …
For Teachers
Tools and resources for teaching the concepts of transcription and translation, two key steps in gene expression
… This list of websites provide tools and resources for teaching the concepts of transcription and translation, … of base pairs in a gene and the corresponding amino acid sequence that it encodes. In the cell cytoplasm, the … thousands of media resources, support materials, and tools for classroom lessons.One of these resources focuses on …
Educational Resources
A promoter is a sequence of DNA needed to turn a gene on or off.
… Deoxyribonucleic Acid (DNA), Enzyme, Gene, Gene Expression, Gene Regulation, …
News Release
A team of NIH-funded researchers have generated the first complete chromosome sequences from non-human primates.
… DNA sequences. These sequences are much more challenging for scientists to characterize, and studying repetitive DNA … has only become possible in recent years due to new DNA sequencing technologies and analysis methods. These … among the primate Y chromosomes is their length. For example, the Y chromosome from the Sumatran orangutan is …
Educational Resources
A restriction enzyme is an enzyme isolated from bacteria that cuts DNA molecules at specific sequences.
… Bacteria, Deoxyribonucleic Acid (DNA), Enzyme, Genetic Engineering, Recombinant DNA …