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News Release
NHGRI has appointed Neil Hanchard, M.D., Ph.D., as a clinical investigator within the Medical Genomics and Metabolic Genetics Branch (MGMGB) in the Division of Intramural Research. Dr. Hanchard will head the Childhood Complex Disease Genomics Section within the MGMGB.
… methods to study several pediatric diseases, including sickle cell disease, severe childhood malnutrition, pediatric HIV in … complex pediatric diseases, diverse populations, sickle cell disease, severe childhood malnutrition, pediatric …
Talking Glossary
Chromosomes are threadlike structures made of protein and a single molecule of DNA that serve to carry the genomic information from cell to cell.
… of DNA that serve to carry the genomic information from cell to cell. … Chromosomes are threadlike structures made of protein … of DNA that serve to carry the genomic information from cell to cell. In plants and animals (including humans), …
Talking Glossary
A gamete is a reproductive cell of an animal or plant.
… Gamete … A gamete is a reproductive cell of an animal or plant. … A gamete is a reproductive cell of an animal or plant. In animals, female gametes are … called sperm. Ova and sperm are haploid cells, with each cell carrying only one copy of each chromosome. During …
News Release
Learn what happens when two genetic neighborhoods merge in brain tumor cells after a gene controlled by a gene-control switch turned on a cancer-growth gene.
Staff
Dr. Neil Hanchard is a clinical investigator within the Center for Precision Health Research (CPHR) and head of the Childhood Complex Disease Genomics Section within the CPHR.
… the unique metabolic disturbances of kwashiorkor. Sickle Cell Disease Alloimmunization Sickle cell disease (SCD) is one of the most common …
Talking Glossary
Methylation is a chemical modification of DNA and other molecules that may be retained as cells divide to make more cells. regulating the production of proteins that the gene encodes.
The Genomics Landscape
In the July 2021 issue of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., reflects on the legacy the LINCS program leaves as it has completed its goal of creating a large-scale, systematically generated molecular and cellular dataset.
… agents and their effects on the development of a cell’s normal state. In addition, LINCS developed a resource … “signatures” that reflect the responses that different cell types show under different conditions. LINCS was based … cellular characteristics, behavior, and/or function of a cell. In the past, most research studies designed to …
Fact Sheets
Chromosomes are thread-like structures located inside the nucleus of animal and plant cells.
… Scientists gave this name to chromosomes because they are cell structures, or bodies, that are strongly stained by some … For example, if all of the DNA molecules in a single human cell were unwound from their histones and placed end-to-end, … produce new cells to replace old, worn-out cells. During cell division, it is essential that DNA remains intact and …
Educational Resources
The genome is the entire set of genetic instructions found in a cell.
… is the entire set of genetic instructions found in a cell. … Genome, Genomics, DNA Sequence, Human Genome Project, … genome is the entire set of DNA instructions found in a cell. In humans, the genome consists of 23 pairs of chromosomes located in the cell’s nucleus, as well as a small chromosome in the cell’s …