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Comparative genomics is a field of biological research in which researchers compare the complete genome sequences of different species.
… Comparative genomics is a field of biological research in which researchers use a variety of tools to … biology of living things have changed over time. As DNA sequencing technology becomes more powerful and less … In recent years, researchers in the National Human Genome Research Institute (NHGRI) intramural program also have …
Research Funding
The Encyclopedia of DNA Elements (ENCODE) Pilot Project launched in September 2003 to identify all functional elements in the human genome sequence.
… The National Human Genome Research Institute (NHGRI) launched a public research consortium named the Encyclopedia of DNA Elements … genome was announced by the International Human Genome Sequencing Consortium ( Finishing the euchromatic sequence of … the NHGRI proposed to create a highly interactive public research consortium to carry out a pilot project for testing …
Research Funding
A collaborative large-scale genome sequencing effort to identify rare risk and protective variants contributing to multiple common disease phenotypes.
… Genomics (CCDG) are a collaborative large-scale genome sequencing effort to comprehensively identify rare risk and … approaches and technologies for multiple disease research communities and the wider biomedical research community. The CCDGs study cardiovascular diseases …
News Release
Baylor College of Medicine. Houston and the Medical College of Wisconsin, Milwaukee will be providing DNA sequencing for the Undiagnosed Diseases Network.
… College of Wisconsin in Milwaukee will be providing DNA sequencing for the Undiagnosed Diseases Network (UDN). Each … The two universities will become the DNA Sequencing Core sites for the UDN. The UDN also includes seven clinical sites at academic medical centers and at the NIH, as …
Research at NHGRI
The NHGRI Division of Intramural Research aims to advance the frontiers of genetics and genomics.
… The goal of the National Human Genome Research Institute's (NHGRI) Division of Intramural Research is to advance the frontiers of genetics and genomics. … projects because of our strengths in basic, clinical, social, and behavioral research. Achieving our …
News Release
NIH researchers have developed and released an innovative software tool, called Verso, to assemble truly complete (i.e., gapless) genome sequences from a variety of species. The software makes the process of assembling complete genome sequences more affordable and accessible.
… collaborative project funded by the National Human Genome Research Institute (NHGRI), part of NIH. “We took everything … complete genome sequence.” The T2T consortium used new DNA sequencing technologies and analytical methods to generate … like putting together a jigsaw puzzle, and different DNA sequencing technologies generate different types of genomic …
Research at NHGRI
In NHGRI, Staff Clinicians work on many different clinical research studies, including helping to better understand, manage, and treat a diverse group of clinical conditions.
… clinically-oriented patient care services as part of research studies. Staff Clinicians are expected to provide clinical leadership and the highest level of clinical care. In NHGRI, Staff Clinicians work on many … In NHGRI, Staff Clinicians work on many different clinical research studies, including helping to better …
Infographic
An infographic that explains why it was so difficult to fully complete the human genome sequence.
… with a vision. Even with new technologies, genome sequencing is still tough, time-consuming work that requires …
News Release
Researchers with support from NIH will conduct research into the genetic underpinnings of Alzheimer's disease.
… support from the National Institutes of Health to conduct research into the genetic underpinnings of Alzheimer's … Texas, Houston. The investigators will analyze the genome sequencing data generated during the first phase of the … primary federal agency conducting and supporting basic, clinical, and translational medical research, and is …
Talking Glossary
While some sequencing technologies produce reads that are only a few hundred nucleotides long, some methods can generate reads that are thousands to hundreds of thousands of nucleotides long, known as “long-read DNA sequencing.”
… Long-Read DNA Sequencing … While some sequencing technologies produce reads that are only a few … of thousands of nucleotides long, known as “long-read DNA sequencing.” … DNA sequencing technologies determine the order of the base pairs … to assemble the sequences of full chromosomes. While some sequencing technologies produce reads that are only a few 100 …