Search Results
The Genomics Landscape
In the October 2019 edition of The Genomics Landscape, NHGRI Director Eric Green focuses on recent efforts to make the human genome reference sequence useful to basic and clinical researchers and how increasing the representation of human genomic variation will remain key components of NHGRI’s Human Genome Reference Program.
… provides comprehensive treatment for inherited blood and immune diseases Genome: Unlocking Life's Code September 2019 …
Educational Resources
AIDS is a collection of symptoms known as acquired immunodeficiency syndrome.
… human immunodeficiency virus (HIV), which leads to loss of immune cells and leaves individuals susceptible to other …
The Genomics Landscape
In the August 2023 edition of The Genomics Landscape, NHGRI Director Eric Green introduces incoming NHGRI DEO Director, Jennifer Troyer.
… Genomics Research Researchers find weaker immune response to viral infections in children with …
Genetic Disorders
Antiphospholipid Syndrome is a disorder characterized by elevated levels of antibodies that are associated with clots in the arteries and veins.
… to its normal size). Thrombocytopenia An association with immune thrombocytopenia (low platelets) has also been … category of autoimmune disorders (conditions caused by an immune response against the body's own tissues). Individuals …
Fact Sheets
Epigenomics is a field in which researchers chart the locations and understand the functions of all the chemical tags that mark the genome.
… can switch on or off genes involved in cell growth or the immune response. These changes can lead to uncontrolled … growth, a hallmark of cancer, or to a failure of the immune system to destroy tumors. In a type of brain tumor called …
News Release
NIH-funded researchers completed the PanCancer Atlas from over 10,000 tumors representing 33 types of cancer.
… to other parts of the body through the circulatory system. Image credit: Darryl Leja, NHGRI. "TCGA was the first … and protein expression; and the interplay of tumor and immune cells. These findings will help prioritize the …
Research Funding
Polygenic RIsk MEthods in Diverse populations (PRIMED) Consortium will work together to develop and implement approaches to integrating extant genotype and phenotype data for the purpose of conducting and disseminating Consortium-wide PRS analyses.
… Scores and Health Disparities: The Role of Blood Cells Immune Response and Evolutionary Adaptation Broad Institute, …
Genetic Disorders
Velocardiofacial syndrome is the most common syndrome associated with a cleft palate.
… of the parathyroid hormone that can result in seizures); immune system problems which make it difficult for the body to fight … aggressively with antibiotics in infants and children with immune problems. Early intervention and speech therapies are …
The Genomics Landscape
In the October 6, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., celebrates the 25th anniversary of the NIH Intramural Sequencing Center (NISC). a well-respected and highly used large-scale DNA sequencing center that exemplifies the evolution of the field of genomics and the ever-increasing abilities to produce prodigious amounts of genomic data.
… the COVID-19 pandemic to sequence SARS-CoV-2 genomes and immune-response transcriptomes collected as part of several …
News Release
Top genome scientists from over 20 countries have joined forces in an effort to improve cooperation and coordination of genomic medicine research worldwide.
… hosted by the Singapore National University Health System. The organizers hope to attract as many as 150 … database of up to 500,000 people. Israel's Clalit health system is providing all medical institutes with … by certain medications in people with high-risk forms of immune-system genes. "Pharmacogenetics cards," similar to …