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Staff
Dr. Marjan Huizing is a staff scientist in the Medical Genetics Branch at the National Human Genome Research Institute.
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… single mutant allele using a synthetic small interfering RNA (siRNA) rescued the abnormal phenotype in cultured cells … silencing of the dominant disease allele in sialuria by RNA interference. FASEB J, 22:3846-3852. 2008. [ PubMed ] …
Staff
Dr. Paul Meltzer is an adjunct investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… and consequences of genome instability, non-coding RNA biology, and translational genomics. Developing …
News Release
The TCGA network describes uterine and bile duct cancer.
… all the key genomic changes - the modifications in DNA, RNA and proteins that cause the uncontrolled cell growth that …
Staff
Dr. Lisa Helbling Chadwick is a deputy director in Division of Genome Sciences at the National Human Genome Research Institute. ​
… genomic technologies related to gene expression or RNA regulation. She also oversees NHGRI’s GREGoR Program, …
News Release
National Institutes of Health researchers have discovered a specific network of proteins that is necessary to restore hearing in zebrafish through cell regeneration. The study may inform the development of treatments for hearing loss in humans.
… researchers used new genomic techniques called single-cell RNA sequencing and single-cell assay for …
Staff
Dr. Randy Chandler is an associate investigator in the Organic Acid Research Section of the Metabolic Medicine Branch in NHGRI.
… startup . Hum Gene Ther. 2020. Chandler RJ. Messenger RNA therapy as an option for treating metabolic disorders . … RJ, Guey LT, Venditti CP, Martini PGV. Systemic messenger RNA therapy as a treatment for methylmalonic acidemia . Cell …
National Advisory Council for Human Genome Research
The Director's Report-Related Documents contain links to materials supplemental to Dr. Eric Green's Director's Report presentation to the National Advisory Council for Human Genome Research in May 2024.
… Rule 12 NASEM Report: Charting a Future for Sequencing RNA and Its Modifications NASEM Report Webinar Associated …
News Release
NIH researchers have successfully identified differences in gene activity in the brains of people with attention deficit hyperactivity disorder (ADHD). The study, led by scientists at the National Human Genome Research Institute (NHGRI), found that individuals diagnosed with ADHD had differences in genes that code for known chemicals that brain cells use to communicate.
… symptoms. The researchers used a genomic technique called RNA sequencing to probe how specific genes are turned on or …