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News Release
Researchers find weaker immune response to viral infections in children with mitochondrial disorders
NIH researchers analyzed the gene activities of immune cells in children with mitochondrial disorders and found that their B cells, which produce antibodies to fight viral infections, are less able to survive cellular stress.
… of Health (NIH) researchers found that altered B cell function in children with mitochondrial disorders led to … in Immunology was led by researchers at the National Human Genome Research Institute (NHGRI), who analyzed gene activity … Mitochondria are important components of nearly every cell in the body because they convert food and oxygen into …
Genomics and Medicine
The NHGRI Genomic Medicine Working Group has compiled a list of interesting advances.
Educational Resources
Centrioles are paired barrel-shaped organelles located in the cytoplasm of animal cells near the nuclear envelope.
… Cell Biology, Organelles, Nucleus … play a role in organizing microtubules that serve as the cell's skeletal system. They help determine the locations of the nucleus and other organelles within the cell. …
Educational Resources
Endoplasmic reticulum is a network of membranes inside a cell through which proteins and other molecules move.
… Endoplasmic reticulum is a network of membranes inside a cell through which proteins and other molecules move. … Cell Biology, Proteins, Nucleus … Endoplasmic reticulum is a network of membranes inside a cell through which proteins and other molecules move. … ribosomes. When proteins are destined to be part of the cell membrane or exported from the cell, the ribosomes …
Educational Resources
Mitosis is a cellular process that replicates chromosomes and produces two identical nuclei in preparation for cell division.
… and produces two identical nuclei in preparation for cell division. … Mitosis, Meiosis, Cell Biology, DNA, Chromosome … Mitosis is the process by which a cell replicates its chromosomes and then segregates them, producing two identical nuclei in preparation for cell division. Mitosis is generally followed by equal …
Educational Resources
Cytoplasm is the gelatinous liquid that fills the inside of a cell. It is composed of water, salts, and various organic molecules.
… is the gelatinous liquid that fills the inside of a cell. It is composed of water, salts, and various organic … Organelles, Mitochondria, Nucleus, Cell Biology … is the gelatinous liquid that fills the inside of a cell. It is composed of water, salts, and various organic …
Health FAQ
Discuss these questions with your doctor or health care provider.
… Education Project welcomes your feedback about the sickle cell disease gene therapy resources. Please email your … your general understanding of gene therapy for sickle cell disease. We encourage you to use these educational … a plan for the treatments you are taking for your sickle cell disease. For example, if you are taking hydroxyurea, you …
News Release
NHGRI researchers have developed the Families Sharing Health Assessment and Risk Evaluation (SHARE) workbook, which helps people use their family history to assess their risk for heart disease, diabetes, breast cancer and colorectal cancer.
… Researchers at the National Human Genome Research Institute (NHGRI), part of the National … to assess their risk for heart disease, diabetes, breast cancer and colorectal cancer. Since 2012, Laura Koehly, Ph.D., and her research … to assess their risk for heart disease, diabetes, breast cancer and colorectal cancer. …
Educational Resources
Endoplasmic reticulum is a network of membranes inside a cell through which proteins and other molecules move.
… Endoplasmic reticulum is a network of membranes inside a cell through which proteins and other molecules move. … Endoplasmic Reticulum, Proteins, Ribosomes, Cell Biology … Endoplasmic reticulum is a network of membranes inside a cell through which proteins and other molecules move. …
Research Funding
MorPhiC aims to develop a consistent catalog of molecular and cellular phenotypes for null alleles for every human gene by using in-vitro multicellular systems.
… regulators U01 HG013175 Wei Sun Fred Hutchinson Cancer Center Statistical Methods for Inferring … gene will be known; for non-coding elements in the human genome, such knowledge will be the rule, rather than the exception.” Systematically obtaining genome-wide information about gene functions is critical for …