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Educational Resources
A trait is a specific characteristic of an organism.
… Traits can be determined by genes, environmental factors or by a combination of both. Traits can be …
Genetic Disorders
Prostate cancer is a disease where certain cells in the prostate become abnormal and multiply to form a tumor.
… have prostate cancer at age 55 or younger. Environmental Factors: Environmental risk factors are associated with developing prostate cancer. These … studies are helping scientists to understand the genetic factors that have a role in inherited risk for prostate …
Educational Resources
NHGRI participates in the South By Southwest (SXSW) conference to help increase genomic literacy.
… over time, used to group people according to various factors. Though these visible traits are influenced by genes, … at ethnicity as the main identifier? Or are there genomic factors that can be used as identity markers? Panelists: …
Talking Glossary
A polygenic risk score (abbreviated PRS) uses genomic information alone to assess a person’s chances of having or developing a particular medical condition.
… genomic variants, without taking environmental or other factors into account. …
Talking Glossary
Phenotypic variance is the observed variability of a particular trait. For many measurable traits (such as height, skin color, and blood pressure) phenotypic variation can be thought of as a distribution.
… often caused by a combination of genetic and environmental factors. …
Research at NHGRI
The Social and Behavioral Research Branch conducts research to apply genomic discoveries to improve health and clinical care.
… a diverse group of disorders and seek to find how genomic factors intersect with, social processes, behavior, and … In doing so, we consider the effect of adverse social factors on gene expression in population groups that are … clients that optimize health outcomes. Further, we study factors that influence a variety of health-related …
The Genomics Landscape
In the July 2021 issue of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., reflects on the legacy the LINCS program leaves as it has completed its goal of creating a large-scale, systematically generated molecular and cellular dataset.
… how these pieces work normally and identifying the factors that disrupt normal function is a central challenge …
News Release
NIH researchers and collaborators have found that that sickle cell trait is prevalent among diverse human populations.
About Genomics
A introduction to basic concepts in genomics to help you understand your genome, how it works, and how it impacts your health.
… give information about your ancestry, kinship, lifestyle factors and potential disease risk. … genes. On top of that, lifestyle and environmental factors play a critical role in your development and health. …
Fact Sheets
Genetics refers to the study of genes and their roles in inheritance. Genomics refers to the study of all of a person's genes (the genome).
… caused more by a combination of genetic and environmental factors than by individual genes. Genomics is offering new … people get sick from certain infections, environmental factors, and behaviors, while others do not. For example, … as falls, motor vehicle accidents or poisoning), genomic factors play a role in nine of the ten leading causes of …