Search Results
Staff
Dr. David Bodine is the chief of and senior investigator in NHGRI's Genetics and Molecular Biology Branch.
… in cells from other lineages. NHGRI’s ENCyclopedia Of DNA Elements (ENCODE) Project was developed to identify all functional elements in the human genome, including epigenetic marks and … LA, Garrett LJ, Elnitski L, Gallagher PG, Bodine DM. Functional analysis of a novel cis-acting regulatory region …
Research Funding
The Non-Coding Variants Program explores which variants in a region associated with a disease or trait cause the higher risk for the disease or trait
… or trait. However, most variants, including most of the functional ones that contribute to disease risk, are not in protein-coding regions. These functional variants generally affect the regulation of genes … Georgia Institute of Technology eQTL mega-analysis for functional assessment of multi-enhancer gene regulation R01 …
National Advisory Council for Human Genome Research
The Director's Report Related documents contain links to materials supplemental to Dr. Eric Green's Director's Report presentation to the National Advisory Council for Human Genome Research in September 2020.
… Description Podcast Series Registration 15 Next Steps for Functional Genomics NASEM Report 16 Heritable Human Genome … Technology Development Meeting 20 ENCyclopedia Of DNA Elements (ENCODE) ENCODE Program Website ENCODE Portal ENCODE … Site ENCODE Participants Search Candidate cis-Regulatory Elements by ENCODE (SCREEN) 21 Impact of Genomic Variation on …
Research Funding
A list of the current courses that are funded by the NHGRI Initiative to Maximize Research Education in Genomics.
… Desert Island Biological Lab CSHL Statistical Methods for Functional Genomics Course The course is designed to build … of computational methods for the characterization of functional elements in DNA and RNA sequence data. The workshop is geared …
Event
Joint workshop featuring overviews of Roadmap Epigenomics and ENCODE resources that are freely available for use by the research community.
… The Encyclopedia of DNA Elements (ENCODE) and the Common Fund-supported Roadmap …
News Release
Supporting early career investigators at the cutting edge of genomics.
… regulate expression of genes and are called regulatory elements. Dr. Pinello’s team will develop approaches to discover and understand how these regulatory elements function and how mutations in these areas can …
FAQ
Questions and answers to help applicants responding to the Pre-Application Webinar for the Building Partnerships and Broadening Perspectives to Advance ELSI Research (BBAER) Program RFA-HG-24-026.
… Program Elements What counts as a relevant community? For purposes … proposal? When aspects of our proposal overlap two or more elements, should we describe them only in one application … will provide narrative information for each of the five Elements A – E within the Research Strategy attachment. Each …
Research Funding
Frequently asked questions specific to the Data Production FOA (RFA-HG-21-029, RFA-HG-21-030 and RFA-HG-21-031) discussed during the MorPhiC pre-application webinar.
… How well-defined does the strategy for functional assays need to be in the proposal? Should one … the overall program goals, at some level, with some elements that are still being tested/evaluated. When you are … that there may be dependencies between different elements (e.g., between alleles and assays, for example). …
Strategic Plan
NHGRI launched a new round of strategic planning to establish a 2020 vision for genomics aimed at accelerating scientific and medical breakthroughs.
… genomic technology development; genomic variation and its functional consequences; interactions between the genome and …
Staff
Dr. Lawrence Brody is a senior investigator in NHGRI's Social and Behavioral Research Branch and director of NHGRI's Division of Genomics and Society.
… disease. In an attempt to understand all of the genetic elements that regulate folate and vitamin B12 metabolism, the … This transdisciplinary project was designed to test some elements of personalized genetic risk profiling by providing … [ PubMed ] Coyne RS, McDonald HB, Edgemon K and Brody LC. Functional characterization of BRCA1 sequence variants using …