Search Results
Educational Resources
Mapping is the process of making a representative diagram cataloging the genes and other features of a chromosome and showing their relative locations.
Educational Resources
A marker is a DNA sequence with a known physical location on a chromosome. Markers can help link an inherited disease with the responsible genes.
… Marker, DNA Sequence, Gene, Inheritance …
Educational Resources
A locus is the specific physical location of a gene or other DNA sequence on a chromosome, like a genetic street address.
… A locus is the specific physical location of a gene or other DNA sequence on a chromosome, like a genetic … Locus, Allele, DNA Polymorphism, Gene, Chromosome … is a physical site or location within a genome (such as a gene or another DNA segment of interest), somewhat like a …
Fact Sheet
Your mental and physical health are deeply connected. Mental health is important for your overall health and quality of life.
… actions you may want to take as you think about receiving gene therapy. …  There are many unknowns about what to expect from gene therapy. Your thoughts, feelings, beliefs and attitudes … care for your mental and physical health as you consider a gene therapy clinical trial.  Focus on your thoughts and …
Educational Resources
A genetic map is a type of chromosome map that shows the relative locations of genes and other important features.
News Release
Genomic variants that increase risk of kidney disease are found in nearly one-third of West Africans
A study from researchers at National Institutes of Health (NIH) and their collaborators revealed a significant genetic risk factor for kidney disease in people of West African ancestry.
… Their study demonstrated that having just one risk variant in a gene known as APOL1 can significantly increase the risk of … is important for the immune system and variants of the gene are linked to increased risk of chronic kidney disease. …
Genetic Disorders
Duchenne muscular dystrophy is a rapidly progressive form of muscular dystrophy caused by a mutation in the DMD gene.
… form of muscular dystrophy caused by a mutation in the DMD gene. … in boys. It is caused by an alteration (mutation) in a gene, called the DMD gene that can be inherited in families in an X-linked … instructions) on a blood sample for changes in the DMD gene can help establish the diagnosis of Duchenne muscular …
Educational Resources
BRCA1 and BRCA2 are the first two genes found to be associated with inherited forms of breast cancer.
Health
A polygenic risk score is one way by which people can learn what their risk of developing a disease is, based on the total number of genomics variants related to the disease.
… into two classes: those that are associated with a single gene and those that are influenced by multiple genes and … abbreviated with the letters A, T, C and G. A genomic variant occurs in a location within the DNA where that code … inherited diseases can be traced to variants in a single gene. Cystic fibrosis, a progressive genetic disease that …
For Teachers
Tools and resources for teaching the concepts of transcription and translation, two key steps in gene expression
… of transcription and translation, two key steps in gene expression . … Transcription is the process of making an RNA copy of a gene sequence. This copy, called a messenger RNA (mRNA) … the relationship between the sequence of base pairs in a gene and the corresponding amino acid sequence that it …