Search Results
Research at NHGRI
The Metabolic, Cardiovascular and Inflammatory Disease Genomics Branch studies the genomic and social determinants of complex diseases.
Research Funding
The centers define the state-of-the-art study designs and methods to find variants and genes underlying Mendelian disorders.
… The National Human Genome Research Institute funded the Centers for Mendelian … In doing so, the CMGs will define the state-of-the-art study designs and methods to find the variants and genes … of the genetic basis of Mendelian disorders using genome-wide approaches, which are more rapid and cost-effective than …
News Release
NIH-led study finds genetic markers that explain up to 12% of the differences between two people’s blood pressure.
… have discovered over 100 new regions of the human genome, also known as genomic loci , that appear to … the researchers combined four large datasets from genome-wide association studies of blood pressure and hypertension. After …
Media Availability
The Cancer Genome Atlas identified molecular subtypes to help clinicians determine which tumors are more aggressive and which will respond to treatment.
… and treatment. … WHAT: Investigators with The Cancer Genome Atlas (TCGA) Research Network identified new molecular … cancer responds differently to particular therapies. The study also showed that BRAF -driven tumors have a broader … by the National Cancer Institute and the National Human Genome Research Institute, both parts of the National …
AnVIL
The Data Use Oversight System (DUOS) is a semi-automated study registration and DAR management service informed by the GA4GH DUO standard, which enables the secondary use of human genomics and other controlled-access data in compliance with the informed consent of a study’s participants.
… manner that is consistent with the informed consent of the study’s participants. The growing demand for … D ata U se O versight S ystem ( DUOS ) is a semi-automated study registration and DAR management service informed by the … and approval times of researcher DARs. … National Human Genome Research Institute (NHGRI) National Institute for …
News Release
NIH researchers compared a new genetic animal model of Down syndrome to the standard model and found the updated version to be enhanced.
… studied Down syndrome mouse model. The results of this study, published in Biological Psychiatry , may help … Development, senior investigator in the National Human Genome Research Institute (NHGRI) Center for Precision Health … copy of over 200 protein-coding genes to that person’s genome, which causes difficulties with learning, speech and …
News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… in humans, according to scientists at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health. … In a study posted online on June 5, 2015, and to be published in the July 2015 issue of Genome Research , the researchers reported that the …
Clinical Research
An Observational Prospective Natural History Study of Metabolism, Infection and Immunity During the COVID19 Pandemic (At-home Participation).
… An Observational Prospective Natural History Study of Metabolism, Infection and Immunity During the … for decline associated with infection. The goal of this study is to compare biomarkers like genetic and immune … related to genetics and infection. … People in this study will: Provide a blood sample Fill out several health …
Research Funding
The Multi-Omics for Health and Disease Consortium aims to advance the application of multi-omic technologies to study health and disease in ancestrally diverse populations.
… environmental exposures, omics, and childhood NAFLD (LEON) Study Disease Study Site** Stephanie Christenson*, Neeta Thakur, Stephanie … NCI … NIEHS … Contributing NIH Institutes: National Human Genome Research Institute (NHGRI) National Cancer Institute …
Research at NHGRI
The Division of Intramural Research conducts scientific studies in NHGRI's labs on and around the NIH campus in Bethesda, Md.
… and genomics by connecting the base pairs of the Human Genome Project to the bedside of those afflicted with a genetic disease. … The National Human Genome Research Institute's (NHGRI) Division of Intramural … genomic data; generation of animal models critical to the study of human inherited disorders; and design of novel …