Search Results
News Release
NIH researchers compared a new genetic animal model of Down syndrome to the standard model and found the updated version to be enhanced.
… studied Down syndrome mouse model. The results of this study, published in Biological Psychiatry , may help … Development, senior investigator in the National Human Genome Research Institute (NHGRI) Center for Precision Health … copy of over 200 protein-coding genes to that person’s genome, which causes difficulties with learning, speech and …
News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… in humans, according to scientists at the National Human Genome Research Institute (NHGRI), part of the National … In a study posted online on June 5, 2015, and to be published in the July 2015 issue of Genome Research , the researchers reported that the … Zebrafish, genome function, human disease genes, Shawn Burgess, …
Clinical Research
An Observational Prospective Natural History Study of Metabolism, Infection and Immunity During the COVID19 Pandemic (At-home Participation).
… An Observational Prospective Natural History Study of Metabolism, Infection and Immunity During the … for decline associated with infection. The goal of this study is to compare biomarkers like genetic and immune … People in this study will: Provide a blood sample Fill out several health …
Research Funding
The Multi-Omics for Health and Disease Consortium aims to advance the application of multi-omic technologies to study health and disease in ancestrally diverse populations.
… environmental exposures, omics, and childhood NAFLD (LEON) Study Disease Study Site** Stephanie Christenson*, Neeta Thakur, Stephanie … of disease in Asthma (EXPAND-Asthma) Center Disease Study Site** Tanika Kelly*, Ana Ricardo, Maria Argos, Hua … to advance the application of multi-omic technologies to study health and disease in ancestrally diverse populations. …
Research at NHGRI
The Division of Intramural Research conducts scientific studies in NHGRI's labs on and around the NIH campus in Bethesda, Md.
… and genomics by connecting the base pairs of the Human Genome Project to the bedside of those afflicted with a … The National Human Genome Research Institute's (NHGRI) Division of Intramural … genomic data; generation of animal models critical to the study of human inherited disorders; and design of novel …
Policy Issues
Clinical research may yield new health-related information about volunteers who have chosen to participate in the studies.
… IRRs are the results for a specific study participant from a scientific investigation. For … participant possesses a particular gene variant under study. IFs are a subset of IRRs-- findings that are not … Lastly, although much has been learned about the human genome, there remains much to be discovered. Genomic …
Fact Sheets
Genomics is the study of all of a person's genes (the genome), including interactions of those genes with each other and with the person's environment.
… Genomics is the study of all of a person's genes (the genome), including … An organism's complete set of DNA is called its genome. Virtually every single cell in the body contains a … billion DNA base pairs, or letters, that make up the human genome. With its four-letter language, DNA contains the …
News Release
National Institutes of Health researchers have published an assessment of 13 studies that took a genotype-first approach to patient care.
… NIH study shows genotype-first approach uncovers new links to … and offered insights into newly described disorders. The study was published in the American Journal of Human Genetics … Ph.D., a genetic counselor at the National Human Genome Research Institute’s (NHGRI) Reverse Phenotyping Core …
Research at NHGRI
The Genetics and Molecular Biology Branch uses genomic technologies to study the human genome and other organisms and disease mechanisms.
… uses state-of-the-art genetic and genomic technologies to study the genomes of humans and other organisms and disease … the latest genomic and genetic technologies to the study of human disease. Our investigators develop and quickly … and Molecular Biology Branch uses genomic technologies to study the genomes of humans and other organisms and disease …
News Release
Diverse populations are still underrepresented in public genomic databases, according to a new study by researchers from the NIH and Harvard Medical School.
… in public genomic databases, according to a new study by researchers from the National Institutes of Health … to European populations in two public databases, the Genome-Wide Association Study Catalog (GWAS) and the database of … in public genomic databases, according to a new study by researchers from the NIH and Harvard Medical School. …