Search Results
Genomics and Medicine
The categories for the notable accomplishments of research are defined as research that uses genomics to generate or study.
… (below) as research that uses genomics to generate or study.  Category Information Content Genomic Medicine … are defined as research that uses genomics to generate or study. … are defined as research that uses genomics to generate or study. …
Fact Sheet
Several regulations and policies stipulate the information that must be given to research participants prior to their enrolling in a study.
… informed choice about whether to participate in a research study.  In the United States, the requirements for obtaining … taken by the U.S. Government during the Tuskegee Syphilis Study from 1932-1972 without the consent of the men involved in the study led to the creation of National Commission for the …
Research at NHGRI
The Metabolic, Cardiovascular and Inflammatory Disease Genomics Branch studies the genomic and social determinants of complex diseases.
Research Funding
The centers define the state-of-the-art study designs and methods to find variants and genes underlying Mendelian disorders.
… The National Human Genome Research Institute funded the Centers for Mendelian … In doing so, the CMGs will define the state-of-the-art study designs and methods to find the variants and genes … of the genetic basis of Mendelian disorders using genome-wide approaches, which are more rapid and …
News Release
NIH issues a final Genomic Data Sharing policy to speed the translation of data into knowledge, improve health and protect patient privacy.
… September 2013. The GDS policy can be traced to the Human Genome Project, completed in 2003, which required rapid and … The GDS policy is an extension of and replaces the Genome-Wide Association Studies (GWAS) data sharing policy. Since 2007, … Genomic data sharing policy, GDS, data to knowledge, Human Genome Project, GWAS policy, dbGaP, Informed consent …
News Release
NIH-led study finds genetic markers that explain up to 12% of the differences between two people’s blood pressure.
… NIH-led study finds genetic markers that explain up to 12% of the … have discovered over 100 new regions of the human genome, also known as genomic loci , that appear to … the researchers combined four large datasets from genome-wide association studies of blood pressure and hypertension. …
AnVIL
The Data Use Oversight System (DUOS) is a semi-automated study registration and DAR management service informed by the GA4GH DUO standard, which enables the secondary use of human genomics and other controlled-access data in compliance with the informed consent of a study’s participants.
… manner that is consistent with the informed consent of the study’s participants. The growing demand for … D ata U se O versight S ystem ( DUOS ) is a semi-automated study registration and DAR management service informed by the … data in compliance with the informed consent of a study’s participants. Four NIH DACs have tested DUOS to …
Media Availability
The Cancer Genome Atlas identified molecular subtypes to help clinicians determine which tumors are more aggressive and which will respond to treatment.
… WHAT: Investigators with The Cancer Genome Atlas (TCGA) Research Network identified new molecular … cancer responds differently to particular therapies. The study also showed that BRAF -driven tumors have a broader … by the National Cancer Institute and the National Human Genome Research Institute, both parts of the National …
News Release
NIH researchers compared a new genetic animal model of Down syndrome to the standard model and found the updated version to be enhanced.
… studied Down syndrome mouse model. The results of this study, published in Biological Psychiatry , may help … Development, senior investigator in the National Human Genome Research Institute (NHGRI) Center for Precision Health … copy of over 200 protein-coding genes to that person’s genome, which causes difficulties with learning, speech and …
News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… in humans, according to scientists at the National Human Genome Research Institute (NHGRI), part of the National … In a study posted online on June 5, 2015, and to be published in the July 2015 issue of Genome Research , the researchers reported that the … Zebrafish, genome function, human disease genes, Shawn Burgess, …