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Educational Resources
An oncogene is a mutated gene that contributes to the development of a cancer.
… An oncogene is a mutated gene that contributes to the development of a cancer. … An oncogene is a mutated gene that has the potential to cause cancer. Before an oncogene becomes mutated, it is … mutated, changing it into an oncogene and causing the cell to divide and multiply uncontrollably. Some oncogenes work …
News Release
Washington University in St. Louis awarded an honorary Doctor of Science to Eric D. Green, M.D., Ph.D., for his contributions to the field of genomics.
… in St. Louis awarded an honorary Doctor of Science degree to Eric D. Green, M.D., Ph.D. , in recognition of his contributions to the field of genomics and its application to medicine. Dr. … the generation and analyses of sequences from targeted genomic regions in evolutionarily diverse species, and …
Educational Resources
Lyonization is commonly known as X-inactivation. In mammals, males receive one copy of the X chromosome while females receive two copies.
… X-linked Disease, X-inactivation, X Chromosome, Y Chromosome, … Lyonization (also called X-inactivation) refers to the normal phenomenon in which one of the two X …
Research at NHGRI
The Democratizing Education for Sickle Cell Disease Gene Therapy project developed patient-focused educational materials for the sickle cell community.
… The Big Picture Sickle cell disease is an inherited disorder caused by a change in the … and Drug Administration (FDA) approved two gene therapies to treat sickle cell disease. More than 50 scientists, … physicians, patients and other experts worked together to develop content for the Democratizing Education for Sickle …
Clinical Research
The Attention Deficit/Hyperactivity Disorder (ADHD) Genetic Research Study explores the genetic factors contributing to ADHD to improve treatment in the future.
… Study is exploring the genetic factors that contribute to ADHD, with the hope of improving treatment for this … ADHD often appears to run in families, and research studies have suggested that there may be a genetic component to this disorder. Individuals diagnosed with ADHD may have …
Clinical Research
The INSIGHTS study is exploring sickle cell disease in adults.
… The Insights into Microbiome and Environmental Contributions to Sickle Cell Disease and Leg Ulcers Study (INSIGHTS) study … disease in adults by looking at many factors, including genomic, microbial, physical and social influences. … Insights Into Microbiome and Environmental Contributions to Sickle Cell Disease and Leg Ulcers Study …
Fact Sheets
Genome-wide association studies involve scanning markers across the genomes of many people to find genetic variations associated with a particular disease​.
… involve scanning markers across the genomes of many people to find genetic variations associated with a particular disease. … the complete sets of DNA, or genomes, of many people to find genetic variations associated with a particular … useful in finding genetic variations that contribute to common, complex diseases, such as asthma, cancer, diabetes, …
News Release
NHGRI researchers have released new educational materials to help the sickle cell disease community learn about gene therapies for the disease.
… Collaborative effort aims to help patients and their support networks navigate emerging developments in gene therapies for sickle cell disease. … New educational materials to help the sickle cell disease community learn about gene therapies for the disease … project creates new educational materials for sickle cell disease community …
Event
A series focusing on a specific topic of genomic research by pairing an early career researcher funded under NHGRI’s Genomic Innovator Award Program with an established researcher whose own contributions have paved the way for the specific research area.
… 2022, NHGRI will host a new seminar series based on its Genomic Innovator Award  Program, which supports innovative … efforts. Each seminar will focus on a specific topic of genomic research by pairing an early career researcher funded … Program with a more senior researcher whose work relates to the research area, to provide additional context. Since …
Research at NHGRI
The NHGRI Division of Intramural Research aims to advance the frontiers of genetics and genomics.
… Institute's (NHGRI) Division of Intramural Research is to advance the frontiers of genetics and genomics. … We aim to be world leaders in the translation of genomic knowledge … times, high-risk strategies that utilize a wide range of genomic, genetic, computational, and high-throughput …