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Genetic Disorders
Prostate cancer is a disease where certain cells in the prostate become abnormal and multiply to form a tumor.
… and tissue around the prostate to check if the cancer cells have spread (called metastasis). Sometimes the surgery … is aimed directly at the tumor to kill the cancer cells. It is also used in later stages of prostate cancer to … ​Prostate cancer is a​ disease where certain cells in the prostate become abnormal and multiply without …
Fact Sheet
mRNA vaccines inject cells with instructions to generate a protein that is normally found on the surface of SARS-CoV-2, the virus that causes COVID-19.
… Key Points mRNA vaccines inject cells with instructions to generate a protein that is … meaning it degrades easily and does not last long inside cells.   By injecting cells with a synthetic mRNA that encodes a viral spike … fat bubbles that surround a segment of mRNA, which provide cells with the instructions to make a certain viral protein. …
Event
Pre-application webinar on for the Molecular Phenotypes of Null Alleles in Cells (MorPhiC) program funding opportunity announcements (FOAs) on September 10, 2021.
… RFA-HG-21-029  - Molecular Phenotypes of Null Alleles in Cells (MorPhiC) Phase 1: Data Production Research and …   RFA-HG-21-030  - Molecular Phenotypes of Null Alleles in Cells (MorPhiC) Phase 1: Data Analysis and Validation Centers …   RFA-HG-21-031  - Molecular Phenotypes of Null Alleles in Cells (MorPhiC) Phase 1: Data Resource and Administrative …
Educational Resources
A lymphocyte is a type of white blood cell that is part of the immune system.
… immune system. There are two main types of lymphocytes: B cells and T cells. The B cells produce antibodies that are used to attack invading …
Educational Resources
Prostate cancer is a disease characterized by uncontrolled cell growth in the prostate gland, which is part of the male reproductive system.
Staff
Dr. Sharon Milgram is an adjunct investigator in the Genetics and Molecular Biology Branch at the National Human Genome Research Institute.
… cell signaling and protein trafficking in polarized cells, including kidney and airway epithelial cells. Epithelial cells form a lining at the surface of the skin and along …
News Release
National Institutes of Health researchers have discovered a specific network of proteins that is necessary to restore hearing in zebrafish through cell regeneration. The study may inform the development of treatments for hearing loss in humans.
…   Confocal image of adult zebrafish hair cells (green) in the auditory organ of the inner ear. Credit: … come from the loss of hearing receptors known as “hair cells” in the inner ear. Bristles that stick out of these … cells start replicating. These support cells are like stem cells because of their ability to become other cell …
Educational Resources
A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli).
… DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli). … DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli). BACs are often used in … with their inserted DNA, are then taken up by bacterial cells. As the bacterial cells grow and divide, they amplify …
Staff
Dr. Settara Chandrasekharappa is an associate investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… in 2009 with a report that menin is required for in vitro hematopoietic differentiation of mouse embryonic stem cells and this role of menin is mediated by its ability to … S, Liu PP, Collins FS, Chandrasekharappa SC. In vitro hematopoietic differentiation of mouse embryonic stem cells
News Release
NIH researchers researchers and collaborators have gained some key insights into the biological inner-workings of regrowing a body, the evolution of aging and a unique method to dispose of aging cells, by studying the genomes of a hermit crab (Hydractinia symbiolongicarpus).
… and corals regrows its entire body with help from “aging” cells. … and age-related diseases. Typically, in humans, senescent cells stay senescent, and these cells cause chronic … researchers found that Hydractinia has a special group of stem cells for regeneration. Stem cells can transform into …