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News Release
NIH Center for Research on Genomics and Global Health is participating in the H3Africa Consortium's effort to develop an African-specific genotyping array.
… the risk of other diseases in Africans and people of African descent. Mutations in the gene APOL1 , for example, … to offer protection against the pathogen that causes African sleeping sickness, but today Africans and people of … characterization of Africans and the people of the African diaspora." Dr. Rotimi is director of the Center for Research …
News Release
More research must be done to understand the interactions of ancient genes with modern environments.
… the risk of other diseases in Africans and people of African descent. Mutations in the gene APOL1 , for example, … to offer protection against the pathogen that causes African sleeping sickness, but today Africans and people of … characterization of Africans and the people of the African diaspora." Dr. Rotimi is director of the Center for Research …
News Release
Researchers have conducted the first study to look at the genomic underpinnings of obesity in continental Africans and African Americans.
… underpinnings of obesity in continental Africans and African Americans. They discovered that approximately 1 percent of West Africans, African Americans and others of African ancestry carry a genomic variant that increases their …
News Release
An international team of researchers including NIH has completed the first comprehensive characterization of genomic diversity across sub-Saharan Africa.
… clues to medical conditions in people of sub-Saharan African ancestry, and indicates that the migration from … data to explore the genomic-variation landscape of several African ethno-linguistic groups. A genotype is a subset of a … ​ … Genomic diversity and sub-Saharan Africa, African diaspora, African genomic research, genotyping in Africa, …
News Release
The largest genomic study on type 2 diabetes in Africans to date has recently been published in Nature Communications and reports the most recent findings of the ongoing Africa America Diabetes Mellitus (AADM) study that has been led by Dr. Charles Rotimi for over two decades.
… of the Genomics of Type 2 Diabetes in Africans Identifies African-specific Risk Locus … The largest genomic study on …
News Release
This publication and the release of the accompanying data address knowledge gaps across genomics and are certain to have a continuing impact in the field.
… in Nature addresses this lack with a study of 426 African individuals, representing 50 ethnolinguistic groups. … with WGS data from the 1000 Genomes Project and the African Genome Variation Project are included for comparison … (grey circles). 1000G, 1000 Genome Project; AGVP, African Genome Variation Project. Figure originally published …
News Release
Researchers identified regions of the genome associated with skin color variation in some African populations, furthering skin disease and cancer research.
… that are associated with skin color variation in some African populations, opening new avenues for research on skin … regions of the human genome associated with skin color in African populations. To do this, they took color meter readings from the inner arms of 2,092 African participants to determine the levels of melanin in …
News Release
NIH-backed African scientists are engaged in a global research endeavor to understand the genetic basis of disease in all populations.
… Sheena Faherty, Ph.D. … NIH-backed African scientists are engaged in a global research endeavor … … A Global Research Endeavor Studies have shown that African populations contain the oldest and most diverse set … populations. By not exploring genetic variation within African populations, opportunities are missed to advance not …
Clinical Research
GENE-FORECAST® is developing a community cohort and resource for defining the significance of ancestry-related genomic variation in African-Americans.
… significance of ancestry-related genomic variation in African-Americans. … GENE-FORECAST® will test the working … between the distinct genomic variation characteristic of African-Americans (AA) and the exposome of social … and phenotypes (e.g. coronary artery calcification) in African-Americans (AA). To examine the associations between …
Staff
Dr. Charles Rotimi is the scientific director of and NIH Distinguished Investigator in the Division of Intramural Research. He also serves as the director of the Center for Research on Genomics and Global Health (CRGGH).
… populations with particular emphasis on populations of the African Diaspora. His team published the first genome-wide scan for hypertension and blood pressure in African Americans and for type-2 diabetes in West Africans. …