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News Release
A genetic mutation that triggers bladder cancer in dogs is identical to a mutation that is implicated in multiple human cancers.
… Mjoseth … Over the years, domestic dogs have figured in medical breakthroughs, whether by mushing across Alaska to … our aid-as a powerful animal model for research into human cancer. … A genetic mutation that triggers bladder cancer in dogs is identical to a mutation that is …
News Release
Investigators with The Cancer Genome Atlas Research Network have identified new potential therapeutic targets for a major form of bladder cancer.
… and Public Liaison Branch … Investigators with The Cancer Genome Atlas (TCGA) Research Network have identified … new potential therapeutic targets for a major form of bladder cancer, including important genes and pathways that are disrupted in the disease. They also discovered that, at the molecular …
News Release
An ancient, sexually transmitted dog cancer may provide insights into human cancers because of the similarities in the dog and human immune systems.
… Steven Benowitz … An ancient, sexually transmitted dog cancer - that may provide insights into human cancers because of the similarities in the dog and human immune systems - has baffled researchers … or bacterium. … By comparing the genomes of 186 healthy dogs from a wide variety of species to two of the dog tumor …
News Release
Experts from The NHGRI Dog Genome Project turned to Reddit to answer questions as part of an "Ask Me Anything".
… Dog Genome Project is to sequence the genomes of 10,000 dogs in the next four years. Dog genomes hold a wealth of … Our AMA hosts were Elaine Ostrander, Ph.D., chief of the Cancer Genetics and Comparative Genomics Branch at NHGRI; …
News Release
NIH researchers have sequenced the whole genome of a dog native to Sardinia, Italy, and discovered in it clues about the migration of humans to the area.
… native to the mountains of Sardinia, Italy, and discovered in it clues about the migration of humans to the area. (A … 12, 2016 in the journal, Genetics . … Called Fonni's Dogs, named for the city of Fonni, these fiercely protective … migrated," said Elaine Ostrander, Ph.D., chief of NHGRI's Cancer Genetics and Comparative Genomics Branch . …
News Release
NHGRI's Dr. Elaine Ostrander and the Smithsonian's Dr. Dennis Stanford discover North America's oldest dog relics, important in canine genome research.
… points - that have been found at their kill sites. … In 1974 Dennis Stanford, Ph.D., archaeologist and director of … Elaine Ostrander, Ph.D., a senior investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch. Dr. … on genes that influence the development of diseases in dogs and humans. Her lecture, The Dog Genome: Shedding Light …
News Release
The finding marks a new effort in conserving an ancient dog breed, with potential to inform human vocalization processes.
… Prabarna Ganguly, Ph.D. … The finding marks a new effort in conserving an ancient dog breed, with potential to inform human vocalization processes. … In a study published in PNAS , researchers used conservation … tonal quality. Only 200-300 captive New Guinea singing dogs exist in conservation centers, with none seen in the …
Genetic Disorders
Breast cancer is the second most common cancer in women after skin cancer.
… Breast cancer is the second most common cancer in women after skin cancer. Each year, approximately …
News Release
NHGRI researchers, collaborators at the University of California (UC) San Diego, UC Davis and the University of Pittsburgh School of Medicine lay out a new framework for comparing dog-to-human aging, one that uses epigenetics as a biological marker to better understand the aging process.
… epigenetic differences between humans and domestic dogs provides an emerging model of aging. … One of the most … is that one human year equals seven dog years in terms of aging. However, this equivalency is misleading … dismissed by veterinarians. A recent study, published in the journal Cell Systems , lays out a new framework for …
Genetic Disorders
Skin cancer is the most common type of cancer in the United States.
… Skin cancer is the most common type of cancer in the United States. An estimated 40 to 50 percent of …