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News Release
Using a recently developed DNA base-editing technique, researchers correct accelerating aging disorder.
… Prabarna Ganguly, Ph.D. … Using a recently developed DNA base-editing technique, researchers correct accelerating aging disorder. … Researchers have successfully used a DNA-editing technique to extend the lifespan of mice with the …
Policy Issues
Patients with genetic disorders and members of the public have diverse about germline genome editing.
… world, have diverse views about whether germline genome editing should be used to prevent or treat genetic disorders. … NIH has  guidelines  stipulating that the NIH Recombinant DNA Advisory Committee will not consider proposals that … [6] Cyranoski, D. (2017). Scientists sound alarm over DNA editing of human embryos. Nature News. …
Policy Issues
Most ethical discussions about genome editing center on human germline editing because changes are passed down to future generations.
… Most of the ethical discussions related to genome editing center around human germline because editing changes … "genome editing" to describe techniques used to modify DNA in the genome. Other groups also use the term "gene … Editing, Gene Therapy, CRISPR, Human Gremline Editing, DNA Editing … Most ethical discussions about genome editing …
Policy Issues
Scientific institutions are developing recommendations to support the responsible use of human gene-editing research.
… decision-making for the responsible use of human genome-editing research. … In light of recent advances in … "genome editing" to describe techniques used to modify DNA in the genome. Other groups also use the term "gene … gene therapy for enhancement purposes. … The  Recombinant DNA Advisory Committee (RAC)  provides the National …
Policy Issues
Genome editing is currently being applied to research on cancer, mental health, rare diseases, and many other disease areas.
… Genome editing is currently being applied to research on cancer, … such as mice or zebrafish. Researchers rely on genome editing tools as a way to explore the connection between  … other disease areas.​ ​ … Genome Editing, Gene Editing, DNA Editing, Gene Therapy, Treating Disease With Gene …
Policy Issues
Scientists have edited genomes for many years, but CRISPR technology has improved the speed, cost, accuracy, and efficiency of genome editing ​
… Techniques to modify DNA in the genome have existed for several decades, but the conversation about the science and ethics of genome editing has grown louder due to faster, cheaper, and more … information between two similar (homologous) strands of DNA. 1  Scientists began developing this technique in the …
Policy Issues
Genome editing is a method that lets scientists change the DNA of many organisms, including plants, bacteria, and animals.
… Genome editing is a method that lets scientists change the DNA of … including plants, bacteria, and animals. Editing DNA can lead to changes in physical traits, like eye color, …
News Release
Researchers show critical association between diabetes and previously unlinked ZRANB3 gene.
… University of Maryland, the researchers used a CRISPR-Cas9 DNA editing system to make the ZRANB3 gene inoperative in …
The Genomics Landscape
In the February 12, 2021 edition of The Genomics Landscape, Dr. Eric Green talks about the 20-year anniversary of the publications that reported the draft human genome sequence.
… laboratory, becoming as straightforward as carrying out a DNA purification . The second session of the series will … a draft ordering of the ~3 billion chemical units in human DNA. It has been a banner year for significant genomics … of autoinflammatory diseases. … Genomics Research DNA-editing method shows promise to treat mouse model of progeria …
Staff
Dr. Michael Erdos is an Associate Investigator in the Molecular Genetics Section of the Center for Precision Health Research.
… transgenic mouse model by inserting a human genomic DNA segment containing the LMNA gene engineered with the … derived from the expression of progerin from human LMNA DNA sequence. In the realm of small molecule therapeutics, … and colleagues are also able to employ CRISPR-based DNA editing to create isogenic iPSC lines for allelic evaluation …