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Educational Resources
Gene regulation is the process of turning genes on and off.
… Gene Regulation … Gene regulation is the process of turning genes … process can be complicated and is carried out by a variety of mechanisms, including through regulatory proteins and …
Research Funding
The Genomics of Gene Regulation project develops methods to construct predictive, accurate gene regulatory network models using genomic data​​.
… in the RFA, individual projects collect genomic data on gene expression, as well as surrogate markers of regulatory elements, in different cell fates or cell … human cell line Michael Snyder, Ph.D. Stanford University Genomics Of Gene Regulation In Progenitor To Differentiated …
News Release
NIH has awarded grants of more than $28 million aimed at deciphering the language of how and when genes are turned on and off.
… Steven Benowitz … The National Institutes of Health has awarded grants of more than $28 million aimed … and off. These awards emanate from the recently launched Genomics of Gene Regulation (GGR) program of the National Human Genome …
Policy Issues
Most genetic tests today are not regulated, meaning that they go to market without any independent analysis to verify the claims of the seller.
… As the field of genomics advances, genetic and genomic tests are becoming … the test predicts the presence or absence of a particular gene or genetic change. Can the test consistently and …
Educational Resources
A tumor suppressor gene directs the production of a protein that is part of the system that regulates cell division.
… Tumor Suppressor Gene … A tumor suppressor gene directs the production of a protein that is part of the system that regulates cell division. … BRCA1, BRCA2, …
News Release
NIH investigators have discovered that genomic switches of a blood cell are key to regulating the human immune system.
… Mjoseth … Investigators with the National Institutes of Health (NIH) have discovered the genomic switches of a … Director, Francis S. Collins, M.D., Ph.D., in the Medical Genomics and Metabolic Genetics Branch at the National Human … called enhancers, which act like switches to control gene activities. Dr. O'Shea's team wondered if the …
News Release
NIH and Inova Health are launching The Genomic Ascertainment Cohort, a pilot project that will examine gene and gene variant influence on phenotypes.
… Exome Aggregation Consortium (ExAC) harbor large numbers of genotypes (an individual's collection of genes). Until … and investigate the health consequences of their genes and gene variants. … Reversing a Long-Standing Paradigm To … M.D., TGAC co-organizer and chief of the Medical Genomics and Metabolic Genetics Branch at NIH's National …
News Release
Grants are awarded to GTEx project to explore human gene expression and regulation in different tissues, and how genomic variation modulates that expression.
… Steven Benowitz … The National Institutes of Health has awarded eight grants as part of the … plays in modulating that expression. … An Atlas of Human Gene Expression The GTEx awards will contribute to a resource … and the proteins that cells produce based on such regulation. To do this, scientists will examine part of the …
News Release
The Encyclopedia of DNA Elements (ENCODE) Project has created a detailed resource on the letters of life, DNA, identifying genes and regions that may regulate genes in the human and mouse genomes.
… third phase offers new insights into the organization and regulation of our genes and genome … The Encyclopedia of DNA Elements … to identify and characterize their functional roles in gene regulation. "A key challenge in ENCODE is that …
News Release
An expert panel from the Clinical Genome Resource (ClinGen) has critically reevaluated the scientific evidence for all 17 reported genes, disputing nine of the genes and revealing only three of the genes to be definitively associated with the most common form of the disease.
… evidence for all 17 reported genes, disputing nine of the genes and revealing only three of the genes to be … reporting to physicians. Published papers reporting gene-disease associations vary widely in their study design … ClinGen is providing much needed clarity for the clinical genomics community regarding which gene-disease pairs have …