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Research Funding
A collaborative large-scale genome sequencing effort to identify rare risk and protective variants contributing to multiple common disease phenotypes.
… the centers for common disease genomics (ccdg) are a collaborative … rare risk and protective variants contributing to multiple common disease phenotypes. … the ccdg initiative explores a range of diseases with the goal of: undertaking variant discovery for …
The Genomics Landscape
In the November 2019 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the International Common Disease Alliance's scientific plenary and launch meeting in September, which included an international panel on opportunities emerging outside the U.S., North America, and Europe; discussions about polygenic risk scores; and an overview about data platforms, data sharing, and ethics.
… institute and the field of genomics. …   the international common disease alliance (icda) was recently established as a … shares many goals with the icda. accelerating progress in common disease genetics discovery and translation is … our common goals of understanding and treating common diseases . …   launched in 2012, the  nhgri history of …
News Release
NHGRI will highlight rare disease research that benefits affected patients and provides insights into more common disorders on Rare Disease Day.
… affected patients and also provides insights into more common disorders.​ … they are underlining this important … that is part of a global effort to raise awareness of rare diseases . several nhgri staff members - anastasia l. wise, … connection between the rare gaucher disease and the more common parkinson's disease . while patients with gaucher …
Policy Issues
Revisions to the Common Rule modernize, simplify, and enhance oversight for human subjects research in the United States.
… the final version of the common rule was published in the federal register on january … nature of research since the original publication of the common rule in 1991. … compliance with the new rules will … studies after the effective date. the changes to the common rule aim to improve informed consent practices with …
News Release
NHGRI will fund a set of genome sequencing and analysis centers whose research will focus on understanding the genomic bases of common and rare human diseases.
… research will focus on understanding the genomic bases of common and rare human diseases . … the national human genome research institute … (nhgri), part of nih, today launched the centers for common disease genomics (ccdg), which will use genome …
News Release
NHGRI researchers have discovered that Mediterranean populations may be more susceptible to an autoinflammatory disease because of evolutionary pressure to survive the bubonic plague.
… prabarna ganguly, ph.d. … genomic variants that cause common periodic fever have spread in mediterranean … by the national institute of allergy and infectious diseases , the national institute of arthritis and … like the plague, is an ancient disease . it is the most common periodic fever syndrome, and symptoms of fmf include …
News Release
Researchers from The Cancer Genome Atlas Research Network identify novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma.
… cancer-causing pathway in lung adenocarcinoma, the most common subtype of lung cancer. knowledge of these genomic … institutes of health. a tcga analysis of another, less common , form of lung cancer, squamous cell carcinoma, was … to understand, diagnose and treat genomic and genetic diseases . additional information about nhgri can be found at …
News Release
NHGRI researchers have discovered clues to the possible cause of recurring, non-contagious fevers and sores that affect only children. Several genes have been implicated with the syndrome, known as PFAPA syndrome (Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis), which could lead to new treatments.
… that also involved sores on the body, including the common canker sore. the study illustrates how long-standing … during flares.” while pfapa syndrome has become the most common recurring fever syndrome in children from western … symptoms between pfapa syndrome and two other inflammatory diseases : behçet’s disease , which causes inflammation of …
News Release
NHGRI researchers asked patients, parents and physicians in the sickle cell disease community (SCD) what they wanted and needed to know about genome editing to make informed decisions about participating in genome-editing clinical trials.
… about nhgri and nih … as genome-editing trials become more common , informed consent is changing … nhgri researchers …
Media Availability
Researchers have used a new combination of microfluidics and genomics to fish out a specific gut bacterium from the sea of microbes in the human microbiome.
… microbiome project (hmp). the hmp is supported by the nih common fund and coordinated by the national human genome … nhgri can be found at http://www.genome.gov . the nih common fund encourages collaboration and supports a series of … the causes, treatments, and cures for both common and rare diseases . for more information about nih and its programs, …